21892-63-7

Usage

Uses

Used in Organic Synthesis:
BIS(1,2-DIPHENYLARSENO)METHANE is used as a Vilsmeier reagent for the preparation of heterocycles and natural products. It aids in the synthesis of complex organic molecules by acting as a reagent that facilitates the formation of desired intermediates.
Used in Organometallic Chemistry:
In organometallic chemistry, BIS(1,2-DIPHENYLARSENO)METHANE serves as a Lewis acid and a ligand. Its ability to accept electron pairs makes it a useful component in the formation of organometallic complexes, which are important in various catalytic processes and materials science.
Used in Pharmaceutical Industry:
Although BIS(1,2-DIPHENYLARSENO)METHANE is highly toxic, its derivatives and related compounds have been studied for their potential applications in the pharmaceutical industry. Researchers are exploring ways to harness its properties while mitigating the risks associated with arsenic compounds.

InChI:InChI=1/C25H22As2/c1-5-13-22(14-6-1)26(23-15-7-2-8-16-23)21-27(24-17-9-3-10-18-24)25-19-11-4-12-20-25/h1-20H,21H2

Upstream product

• 30077-57-7 methylenebis(dichloroarsine) 
• 108-86-1 bromobenzene 
• 75-09-2 dichloromethane 
• 20738-31-2 hexaphenylcyclohexaarsane 
• 591-51-5 phenyllithium 
• 712-48-1 chlorodiphenylarsine 
• 100-63-0 phenylhydrazine 
• 3095-87-2 bromodiphenylarsine 
• 82941-35-3 (diphenylarsino)methyl iodide 
• 21498-51-1 Potassium Diphenylarsenide 
• 856837-45-1 (diphenylarsino-methyl)-diphenyl-arsine oxide 

Downstream Products

• 945-48-2 diphenylmethylarsine 
• 38563-45-0 Diphenylbutylarsine 
• 69289-43-6 C₂₅H₂₂As₂S₂ 
• 28336-06-3 OAs(C₆H₅)2CH₂As(C₆H₅)2O 
• 130144-44-4 1,2-μ-{bis(diphenylarsino)methane-As,As'}-1,1,1,2,2,2,3,3,3,3-decacarbonyl-triangulo-triruthenium(0) 
• 121289-45-0 fac-{bis(diphenylarsino)methane}{bis(diphenylphosphino)methane}tricarbonylmolydenum 
• 128844-70-2 {Ru2(CO)4(μ-O2CMe)2(Ph2AsCH2AsPh2)}n 
• 124826-16-0 Re₂Cl₄((C₆H₅)2AsCH₂As(C₆H₅)2)2 
• 124826-17-1 Re₂Br₄(dpam)2 

Relevant academic research and scientific papers

Construction of a bidentate arsenic ligand library starting from a cyclooligoarsine

Bidentate ligands are, needless to say, pivotal in organo-metallic chemistry. In contrast to phosphorus ligands, practical synthetic protocols for the arsenic analogues remain to be developed, resulting in a lack of bidentate arsenic ligands. Herein the methods that we have recently developed were applied for bidentate arsenic ligands whose frameworks are well known in phosphorus ligand systems such as dppe, dppp, dppf, xantphos, etc. The palladium dichloride complexes of the obtained ligands were synthesized and used for the Suzuki-Miyaura coupling reaction.

New Reagents, XXXIV. (Diphenylarsino)methyllithium: Synthesis and Preparative Applications

(Diphenylarsino)methyl iodide (3) was synthesized for the first time (76 percent). (Diphenylarsino)methyllithium (2), stable at 20 deg C, is accessible from 3 (ca. 100 percent) by iodine-lithium exchange with butyl- or phenyllithium and by organoelement-lithium exchange with butyllithium from diphenylarsane (4d; 92 percent). 2, prepared from 4d, gives far better yields of (diphenylarsino)alkanes by the reaction with alkyl halides than 2, obtained from 3.To the contrary, no difference is observed in the reactivity of 2 from 3 or 4d towards aldehydes and ketones.