218937-72-5

Upstream product

• 142924-31-0 S-ethyl 4,6-O-benzylidene-1-thio-α-D-mannopyranoside 
• 824-94-2 p-methoxybenzyl chloride 
• 100-39-0 benzyl bromide 
• 454664-77-8 ethyl 4,6-O-benzylidene-3-O-p-methoxybenzyl-1-thio-α-D-mannopyranoside 

Downstream Products

• 1235137-06-0 2-O-benzyl-4,6-O-benzylidene-3-O-(p-methoxybenzyl)-α-D-mannopyranosyl trichloroacetimidate 
• 454664-79-0 ethyl O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1->3)-2-O-benzyl-4,6-O-benzylidene-1-thio-α-D-mannopyranoside 
• 454664-78-9 ethyl 2-O-benzyl-4,6-O-benzylidene-1-thio-α-D-mannopyranoside 

Relevant academic research and scientific papers

Synthesis of the tetrasaccharide Glc α (1→3) Man α (1→2) Man α (1→2) Man α (OMe) as inhibitor of calnexin binding to GlcMan9GlcNAc2

Tetrasaccharide GlcMan3 is an inhibitor of GlcMan9GlcNAc2 binding to calnexin, a chaperone protein involved in CFTR-ΔF 508 retention. A convergent route to its methyl glycoside, the title tetrasaccharide, was developed. Th