454664-78-9

Upstream product

• 100-39-0 benzyl bromide 
• 142924-31-0 S-ethyl 4,6-O-benzylidene-1-thio-α-D-mannopyranoside 
• 1541195-05-4 ethyl 2-O-benzyl-4,6-O-benzylidene-3-O-picoloyl-1-thio-α-D-mannopyranoside 
• 32934-24-0 S-ethyl 2,3,4,6-tetra-O-acetyl-1-deoxy-1-thio-α-D-mannopyranoside 
• 454664-77-8 ethyl 4,6-O-benzylidene-3-O-p-methoxybenzyl-1-thio-α-D-mannopyranoside 
• 218937-72-5 ethyl 2-O-benzyl-4,6-O-benzylidene-3-O-p-methoxybenzyl-1-thio-α-D-mannopyranoside 
• 100-52-7 benzaldehyde 
• 7473-36-1 ethyl 1-thio-α-D-mannopyranoside 

Downstream Products

• 876405-34-4 2-(trimethylsilyl)ethyl 3-O-acetyl-2-O-benzyl-4,6-O-benzylidene-β-D-mannopyranosyl-(1->4)-2,3-di-O-benzyl-6-O-(4-methoxybenzyl)-β-D-glucopyranoside 
• 876405-36-6 tert-butyl 3-O-acetyl-2-O-benzyl-4,6-O-benzylidene-β-D-mannopyranosyl-(1->4)-[2-(trimethylsilyl)ethyl 2,3-di-O-benzyl-β-D-glucopyranosid]uronate 
• 876405-37-7 tert-butyl 2-O-benzyl-4,6-O-benzylidene-β-D-mannopyranosyl-(1->4)-[2-(trimethylsilyl)ethyl 2,3-di-O-benzyl-β-D-glucopyranosid]uronate 
• 876405-31-1 2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl-(1->3)-2-O-benzyl-4,6-O-benzylidene-1-thio-α-D-mannopyranosyl trichloroacetimidate 
• 876405-35-5 2-(trimethylsilyl)ethyl 3-O-acetyl-2-O-benzyl-4,6-O-benzylidene-β-D-mannopyranosyl-(1->4)-2,3-di-O-benzyl-β-D-glucopyranoside 
• 876405-30-0 (2R,4aR,6S,7S,8S,8aR)-7-Benzyloxy-2-phenyl-8-((2S,3R,4R,5S,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-hexahydro-pyrano[3,2-d][1,3]dioxin-6-ol 
• 876405-33-3 ethyl 3-O-acetyl-2-O-benzyl-4,6-O-benzylidene-α-D-mannopyranosyl trichloroacetimidate 
• 876405-29-7 ethyl 2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl-(1->3)-2-O-benzyl-4,6-O-benzylidene-1-thio-α-D-mannopyranoside 
• 521309-20-6 ethyl 3-O-acetyl-2-O-benzyl-4,6-O-benzylidene-1-thio-α-D-mannopyranoside 
• 454664-79-0 ethyl O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1->3)-2-O-benzyl-4,6-O-benzylidene-1-thio-α-D-mannopyranoside 

Relevant academic research and scientific papers

Picoloyl protecting group in synthesis: Focus on a highly chemoselective catalytic removal

The picoloyl ester (Pico) has proven to be a versatile protecting group in carbohydrate chemistry. It can be used for the purpose of stereocontrolling glycosylations via an H-bond-mediated Aglycone Delivery (HAD) method. It can also be used as a temporary protecting group that can be efficiently introduced and chemoselectively cleaved in the presence of practically all other common protecting groups used in synthesis. Herein, we will describe a new method for rapid, catalytic, and highly chemoselective removal of the picoloyl group using inexpensive copper(ii) or iron(iii) salts. This journal is

Synthesis of the tetrasaccharide Glc α (1→3) Man α (1→2) Man α (1→2) Man α (OMe) as inhibitor of calnexin binding to GlcMan9GlcNAc2

Tetrasaccharide GlcMan3 is an inhibitor of GlcMan9GlcNAc2 binding to calnexin, a chaperone protein involved in CFTR-ΔF 508 retention. A convergent route to its methyl glycoside, the title tetrasaccharide, was developed. Th

PARTIAL SUBSTITUTION OF THIOGLYCOSIDES BY PHASE TRANSFER CATALYZED BENZOYLATION AND BENZYLATION

Partial substitution by phase transfer catalysis giving monobenzoylated and monobenzylated products from 2,3- and from 4,6-diols in ethyl 1-thio-D-hexopyranosides with the β-gluco, β-galacto- and α-manno-configurations are described.Two disaccharide thiog