219788-64-4

Upstream product

• 219788-52-0 (2R,4R)-4-Allyl-3-benzoyl-4-benzyl-2-phenyl-oxazolidin-5-one 
• 113806-30-7 (2R,4S)-3-benzoyl-4-benzyl-2-phenyloxazolidin-5-one 
• 63-91-2 L-phenylalanine 
• 106-95-6 allyl bromide 
• 219788-58-6 (R)-2-Benzoylamino-2-benzyl-pent-4-enoic acid methyl ester 
• 100-52-7 benzaldehyde 

Downstream Products

• 219788-71-3 (2R)-1-benzoyl-2-benzyl-1,2,3,6-tetrahydro-pyridine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and solid state conformation of phenylalanine mimetics constrained in a proline-like conformation.

We present the synthesis of five- and six-membered cyclic phenylalanine mimics (1, 9, 16 and 17) that are constrained in a proline-like conformation. The five-membered mimetic 16 was prepared by Ring Closing Metathesis (RCM) of diene 15, itself prepared b

Synthesis and X-ray structure of a 1,2,3,6-tetrahydropyridine-based phenylalanine mimetic

A ring-closing metathesis reaction on methyl (2R)-(N-allyl-N- benzoylamino)-2-benzylpent-4-enoate 5, prepared as a single isomer from L- phenylalanine, gave a conformationally restricted 1,2,3,6- tetrahydropyridine-based phenylalanine mimetic 6 in good yi