219788-71-3Relevant academic research and scientific papers
Synthesis and solid state conformation of phenylalanine mimetics constrained in a proline-like conformation.
Gardiner, James,Abell, Andrew D
, p. 2365 - 2370 (2007/10/03)
We present the synthesis of five- and six-membered cyclic phenylalanine mimics (1, 9, 16 and 17) that are constrained in a proline-like conformation. The five-membered mimetic 16 was prepared by Ring Closing Metathesis (RCM) of diene 15, itself prepared b
Synthesis and X-ray structure of a 1,2,3,6-tetrahydropyridine-based phenylalanine mimetic
Abell, Andrew D.,Gardiner, James,Phillips, Andrew J.,Robinson, Ward T.
, p. 9563 - 9566 (2007/10/03)
A ring-closing metathesis reaction on methyl (2R)-(N-allyl-N- benzoylamino)-2-benzylpent-4-enoate 5, prepared as a single isomer from L- phenylalanine, gave a conformationally restricted 1,2,3,6- tetrahydropyridine-based phenylalanine mimetic 6 in good yi
