220368-29-6

Basic information

• Product Name: 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole
• Synonyms: 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole;3-(2-nitrobenzyloxy)-1-(4-chlorophenyl)-1H-pyrazole;1-(4-CHLOROPHENYL)-3-((2-NITROBENZYL)OXY)-1H-PYRAZOLE
• CAS NO: 220368-29-6
• Molecular Formula: C₁₆H₁₂ClN₃O₃
• Molecular Weight: 329.73778
• Mol File: 220368-29-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 483.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.36
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly); Methanol (Slightly)
• PKA: -0.39±0.10(Predicted)
• CAS DataBase Reference: 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole(220368-29-6)
• EPA Substance Registry System: 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole(220368-29-6)

Safety Data

• Hazardous Substances Data: 220368-29-6(Hazardous Substances Data)

Usage

Description

1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole is a chemical compound characterized by its unique molecular structure, which features a pyrazole core with a 4-chlorophenyl group at the 1-position and a (2-nitrophenyl)methoxy group at the 3-position. 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole is known for its potential applications in various industries, particularly as an intermediate in the synthesis of specific fungicides.

Uses

1. Used in Agricultural Industry:
1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole is used as an intermediate for the synthesis of Pyraclostrobin-d6 (P840402), which is an isotope-labelled fungicide. The application reason is to provide effective control of fungal diseases in seed grass and food crops, ensuring better crop yield and quality.
2. Used in Chemical Synthesis:
In the field of chemical synthesis, 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1H-pyrazole serves as a key intermediate for the production of various compounds with potential applications in different industries. Its unique structure allows for further functionalization and modification, making it a valuable building block in the synthesis of new molecules with desired properties.

Upstream product

• 88-72-2 1-methyl-2-nitrobenzene 
• 76205-19-1 1-(para-chlorophenyl)-3-hydroxypyrazole 
• 29872-21-7 o-nitrobenzyl iodide 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 106-39-8 bromochlorobenzene 
• 88-73-3 2-Chloronitrobenzene 
• 612-23-7 2-nitrobenzyl chloride 
• 79-06-1 2-propenamide 
• 1269247-81-5 3-(2-nitrobenzyloxy)-1H-pyrazole 
• 637-87-6 1-Chloro-4-iodobenzene 

Downstream Products

• 222838-33-7 2-(((1-(4-chlorophenyl)-1Hpyrazol-3-yl)oxy)methyl)aniline 
• 220898-42-0 N-hydroxy-N-2-[(N-p-chlorophenyl)-3-pyrazolyloxymethyl]phenyl hydroxylamine 
• 175013-18-0 pyraclostrobin 

Relevant articles and documents

A multiplex lateral flow immunochromatography assay for the quantitative detection of pyraclostrobin, myclobutanil, and kresoxim-methyl residues in wheat

We produced three monoclonal antibodies with high specificity and sensitivity, and developed a lateral flow immunochromatography assay (LFIA) for the qualitative and quantitative detection of pyraclostrobin (PYR), myclobutanil (MYC), and kresoxim-methyl (KRE) in wheat. In the qualitative analysis, the cut-off values of LFIA were 400, 200, and 800 ng/g for PYR, MYC, and KRE in wheat, respectively. Based on the results obtained from the membrane strip reader, we generated calibration curves for the quantitative analysis. PYR, MYC, and KRE monoclonal antibodies (mAbs) had half maximal inhibitory concentrations (IC50) of 25.4, 17.7, and 94.6 ng/g, respectively, and limit of detection (LOD) of 2.5, 2.0, and 8.8 ng/g, respectively. The linear detection scopes were 5.6–116.5, 4.2–74.4, 23.4–383.3 ng/g for PYR, MYC, and KRE, respectively. The intra-assay recoveries ranged from 89.2% to 101.7%, and the coefficients of variation ranged from 4.6% to 6.5%. The inter-assay recoveries ranged from 88.7% to 102.7%, with the coefficients of variation ranged from 7.2% to 9.1%. Thus, our developed LFIA is suitable for the qualitative and quantitative detection of PYR, MYC, and KRE residues in wheat.

Substituted amide compound and preparation method and application thereof

The invention belongs to the technical field of bactericides, and particularly relates to an amide compound represented by a formula (I) in the specification or a pharmaceutically acceptable salt thereof. The compound of the formula (I) shows good activit

Preparation method for high-purity pyraclostrobin

The invention relates to the technical field of compound synthesis, in particular to a preparation method for high-purity pyraclostrobin. The pyraclostrobin is synthesized from p-chloroaniline and o-nitrosotoluene as initial raw materials through the steps of diazotizing, cyclizing, oxidizing, bromizing, condensating, reducing, acylating, methylating and the like. According to the preparation method, the problem that the purity of the pyraclostrobin in the prior art is low is solved; and the preparation method for the pyraclostrobin has the advantages of high yield, high purity and high material utilization rate.