22076-54-6

Usage

Uses

Used in Food Industry:
(2S,3S,4S,5S)-2,3,4,5-Tetrahydroxyhexanedioic acid is used as a low-calorie sweetener for its natural sweetness, providing an alternative to traditional sugar without the associated calories.
Used in Pharmaceutical Industry:
(2S,3S,4S,5S)-2,3,4,5-Tetrahydroxyhexanedioic acid is used as a medicinal compound for its antioxidant and anti-inflammatory effects, offering potential therapeutic benefits in various health applications.
Used in Biochemistry Research:
(2S,3S,4S,5S)-2,3,4,5-Tetrahydroxyhexanedioic acid is used as a subject of study for its unique stereochemistry and role in metabolic pathways, contributing to the understanding of biochemical processes and the development of new pharmaceuticals.

Upstream product

• 3458-28-4 D-Mannose 
• 69-65-8 mannitol 
• 2900-01-8 D-mannaro-1,4:6,3-dilactone 
• 7697-37-2 nitric acid 
• 26301-79-1 D-mannono-1,4-lactone 
• 642-99-9 mannonic acid 
• 7732-18-5 water 
• 530-26-7 D-Mannose 
• 133-42-6 gluconic acid 
• 551-72-4 inositol 
• 87-89-8 D-myo-inositol 
• 3588-17-8 (2E,4E)-2,4-hexadienedioic acid 
• 98221-46-6 Tetra-O-acetyl-dialdehydo-DL-ido-hexodialdose 
• 64-19-7 acetic acid 

Downstream Products

• 3238-40-2 furan-2,5-dicarboxylic acid 
• 2900-01-8 D-mannaro-1,4:6,3-dilactone 
• 7404-38-8 idaric acid bis-(N'-phenyl-hydrazide) 
• 80876-58-0 L-idaric acid 
• 33012-63-4 galactaric acid 
• 576-37-4 DL-altruronic acid 
• 113973-57-2 tetra-O-acetyl-allo-mucic acid 
• 5469-75-0 (2R,3S,4R,5S)-2,3,4,5-tetraacetoxyhexanedioic acid 

Relevant academic research and scientific papers

Modifications in the nitric acid oxidation of D-mannose: X-ray crystal structure of N,N0-dimethyl D-mannaramide

Nitric acid oxidation of D-mannose was carried out under an oxygen atmosphere using a computer controlled reactor. The process represents a catalytic oxidation of D-mannose with oxygen as the terminal oxidant. The crude oxidation product was esterified with methanolic HCl and the esterified product directly converted to crystalline N,N0-dimethyl-D-mannaramide with methylamine. Treatment of the diamide in aqueous sodium hydroxide gave solid disodium D-mannarate. The X-ray crystal structure of N,N0-dimethyl-D-mannaramide was determined as a model for the repeating D-mannaramide units of stereoregular poly(alkylene-D-mannaramides). Disodium D-mannarate was prepared as a precursor of esterified D-mannaric acid for use as a reactive diacid monomer to prepare poly-D-mannaramides.

Kinetics and mechanism of the oxidation of ethyl glycol, D-mannitol and D-sorbitol by hexacyanoferrate(III) ion in aqueous alkaline medium

The rate of oxidation of ethyl glycol, D-mannitoI and D-sorbitol by hexacyanoferrate(III) ion in aqueous alkaline medium is directly proportional to the organic substrate and hydroxide ion concentrations. The dependence of rate on hexa-cyanoferrate(III) ion is nearly first order at lower concentrations and tends towards zero order at higher concentrations. A probable reaction mechanism has been suggested.