22085-94-5Relevant articles and documents
Heterogeneous Catalysis with Basic Compounds to Achieve the Synthesis and C-N Cleavage of Azetidin-2-ones under Microwave Irradiation
Alcaraz, Yolanda,Cruz, Francisco,De La Cruz, Fabiola N.,Delgado, Francisco,Domínguez, José Manuel,Galván, Adriana,Gomez, Clarisa Villegas,Martínez, Merced,Vázquez, Miguel A.
, p. 3625 - 3637 (2019/09/30)
The synthesis of azetidin-2-ones with a completely heterogeneous catalysis is reported. The use of basic compounds as solid catalysts allowed for the synthesis of azetidin-2-ones under microwave irradiation without organic additives such as triethylamine. An excellent catalyst for this transformation was Mg-Al hydroxide (MAH). The present methodology offers the advantages of non-hazardous reaction conditions, short reaction times, high yields, and catalyst reusability. Different substitution groups were tested on the imines and acyl chlorides to explore the scope of the reaction. Unconventional N-C4 bond cleavage was detected in azetidin-2-ones. MAH was characterized by N 2 adsorption-desorption, X-ray diffraction (XRD), scanning electron microscopy (SEM), and high-resolution transmission electron microscopy (HR-TEM).
ELECTROCHEMICAL STUDIES ON Β-LACTAMS. PART 4. ELECTROACETYLATION OF Β-LACTAMS.
Casadei, Maria Antonietta,Inesi, Achille,Moracci, Franco Micheletti,Occhialini, Donatella
, p. 6885 - 6890 (2007/10/02)
Electroreduction of 3-bromo- and 3,3-dichloro-β-lactams 1 carried out at the potential of the first voltammetric peak and in the presence of acetic anhydride gives 3-acetyl-β-lactams 2.The electrosynthesis is highly stereoselective, as only the acetyl der
Reactions of (E)-1-Methoxy-1-trimethylsiloxyprop-1-ene with Acyl Isocyanates and Acyl Isothiocyanates
Cambie, Richard C.,Davis, Paul F.,Rutledge, Peter S.,Woodgate, Paul D.
, p. 2073 - 2084 (2007/10/02)
Reaction of aryl acyl,and alkyl acyl isocyanates with (E)-1-methoxy-1-trimethylsiloxyprop-1-ene affords high yields of various methyl 3-acylamino-2-methyl-3-oxopropanoates.The corresponding acyl isothiocyanates give a variety of products depending on the structure of the isothiocyanate.
