22094-18-4

Basic information

• Product Name: 1,3-Dibromo-2,2-dimethoxypropane
• Synonyms: AKOS BBS-00001922;1,3-DIBROMO-2,2-DIMETHOXYPROPANE;1,3-Dibromoacetone dimethyl acetal;1,3-DIBROMO-2,2-DIMETHOXY-PROPANE 98%;1,3-0DIBROMO-2,2-DIMETHOXYPROPANE;1,3-Dibromo-2,2-dimethoxypropane,99%;1,3-DibroMo-2,2-diMethoxy...;1,3-DibroMoacetone DiMethyl Ketal
• CAS NO: 22094-18-4
• Molecular Formula: C₅H₁₀Br₂O₂
• Molecular Weight: 261.94
• EINECS: -0
• Product Categories: API intermediates
• Mol File: 22094-18-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 65-68 °C
• Boiling Point: 235°C (rough estimate)
• Flash Point: 100.1 °C
• Appearance: White/Crystalline Powder
• Density: 1.8049 (rough estimate)
• Vapor Pressure: 0.0281mmHg at 25°C
• Refractive Index: 1.5120 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• BRN: 1698992
• CAS DataBase Reference: 1,3-Dibromo-2,2-dimethoxypropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dibromo-2,2-dimethoxypropane(22094-18-4)
• EPA Substance Registry System: 1,3-Dibromo-2,2-dimethoxypropane(22094-18-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 22094-18-4(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

InChI:InChI=1/C5H10Br2O2/c1-8-5(3-6,4-7)9-2/h3-4H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 67-64-1 acetone 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 1432048-81-1 {3,3-dimethoxy-1-[4-(trifluoromethoxy)phenyl]cyclobutyl}(pyridin-2-yl)-methanone 
• 1432048-78-6 methyl 3,3-dimethoxy-1-[4-(trifluoromethoxy)phenyl]cyclobutane-carboxylate 
• 1432048-75-3 {3,3-dimethoxy-1-[4-(trifluoromethoxy)phenyl] cyclobutyl}(pyridin-2-yl)-methanol 
• 1432048-10-6 1-(3,4-dichlorophenyl)-3,3-dimethoxycyclobutanecarboxamide 
• 1432048-77-5 3,3-dimethoxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarboxamide 
• 1432048-46-8 3,3-dimethoxy-1-(3-(trifluoromethoxy)phenyl)cyclobutanecarboxamide 
• 1313441-70-1 2-(1-(4-bromophenyl)-3,3-dimethoxycyclobutyl)isoindoline-1,3-dione 
• 1313441-69-8 1-(4-bromophenyl)-3,3-dimethoxycyclobutanamine 
• 1313441-68-7 1-(4-bromophenyl)-3,3-dimethoxycyclobutanecarboxamide 
• 872614-36-3 1-(4-bromophenyl)-3,3-dimethoxycyclobutane-1-carbonitrile 
• 89280-54-6 3,3-dimethoxythietane 
• 1190643-82-3 1-(4-chloro-phenyl)-3-methoxy-cyclobut-2-enecarbonitrile 
• 115118-68-8 3,3-dimethoxycyclobutane-1,1-dicarboxylic acid diisopropyl ester 
• 766513-35-3 C₁₃H₁₅NO₂ 

Relevant articles and documents

Chlorination of Aliphatic Ketones in Methanol

The chlorination of aliphatic ketones in methanol has been examined.The product distributions in methanol differ substantially from those obtained by chlorination in carbon tetrachloride.The reaction in methanol favors addition of chlorine to the least substituted carbon α to the carbonyl group.The effect is especially pronounced if an α carbon bearing two substituents is present.The distribution of products is determined by the relative stability of the enol ethers formed from the ketone under the reaction conditions.