22101-10-6

Upstream product

• 119-61-9 benzophenone 
• 127-19-5 N,N-dimethyl acetamide 
• 124-40-3 dimethyl amine 
• 1061490-12-7 3,3-diphenyl-N-(quinolin-8-yl)propanamide 
• 781-35-1 1,1-diphenylacetone 
• 100780-08-3 3-(3,3-diphenylpropionoxy-)-4-methylthiazole-2(3H)-thione 
• 1608-26-0 Hexamethylphosphorous triamide 
• 530-48-3 1,1-Diphenylethylene 
• 68-12-2 N,N-dimethyl-formamide 
• 623-26-7 terephthalonitrile 
• 37089-77-3 3,3-diphenylpropanoyl chloride 
• 33718-91-1 1,1-diphenyl-1-bromo-2-propanone 

Downstream Products

• 20017-67-8 3,3-diphenylpropan-1-ol 

Relevant academic research and scientific papers

Synthesis method of N,N-dialkyl diphenyl propionamide

The invention discloses a synthesis method of N,N-dialkyl diphenyl propionamide. The method is characterized by accelerating coupling reaction of diphenylketone and N,N-dialkyl acetamide under the action of p-toluenesulfonic acid in the absence of solvent

A Two-Step Procedure for the Overall Transamidation of 8-Aminoquinoline Amides Proceeding via the Intermediate N -Acyl-Boc-Carbamates

Herein a two-step strategy for achieving overall transamidation of 8-aminoquinoline amides has been explored. In this protocol, the 8-aminoquinoline amides were first treated with Boc2O and DMAP to form the corresponding N-acyl-Boc-carbamates,

Synthetic routes for a new family of chiral tetradentate ligands containing pyridine rings

A series of new tetradentate ligands containing two bipyridine groups or two pyridine moieties carrying amine substituents has been synthesised either from 5′- and 6′-substituted chiral bipyridines, or from chiral pyridine derivatives. These precursors ha

Photoinduced Nucleophilic Addition of Ammonia and Alkylamines to Aryl-Substituted Alkenes in the Presence of p-Dicyanobenzene

The photoamination of 1,1-diphenylpropene (1a) with ammonia and some primary alkylamines in the presence of p-dicyanobenzene gave the corresponding N-substituted 2-amino-1,1-diphenylpropane (2a-e) along with the formation of 3-methyl-4,4-diphenylbutanenitrile (3a), 1,1-diphenylpropane (4a), 3,3-diphenylpropene (5), and diphenylmethane (6).In the case of 1,1-diphenylethene (1b), N-substituted 1-amino-2,2-diphenylethane (2f-h), 4,4-diphenylbutanenitrile (3b), and 1,1-diphenylethane (4b) were produced.In photoamination with t-butylamine in acetonitrile, 3a and 3b were mainly formed as a consequence of the incorporation of acetonitrile to 1a and 1b.The photoamination of 1-phenyl-3,4-dihydronaphthalene (1c) with isopropylamine or t-butylamine gave cis- and trans-N-substituted 1-phenyl-2-amino-1,2,3,4-tetrahydronaphthalenes (15 and 16) in a ratio of ca. 8:2.The mechanism of photoamination is discussed in terms of a photochemical electron transfer of 1 to p-dicyanobenzene followed by a nucleophilic addition of the amine to the cation radical of 1.

RADICAL DECARBOXYLATIVE PHOSPHORYLATION OF CARBOXYLIC ACIDS

Thiohydroxamic carboxylic mixed anhydrides (e.g. 1) react at room temperature with (PhS)3P to give, through a decarboxylative phosphorylation reaction, the corresponding dithiophosphonates 12 in moderate yields.