221087-47-4

Basic information

• Product Name: N-(6-BROMOPYRIDIN-2-YL)PIVALAMIDE
• Synonyms: N-(6-BROMOPYRIDIN-2-YL)PIVALAMIDE;N-(6-Bromopyridin-2-yl)-2,2-dimethylpropanamide;N-(6-BroMopyridin-2-yl)-2,2-diMethylpropionaMide;N-(6-bromo-2-pyridinyl)-2,2-dimethylPropanamide;2-(trimethylacetylamino)-6-bromopyridine;Propanamide, N-(6-bromo-2-pyridinyl)-2,2-dimethyl-
• CAS NO: 221087-47-4
• Molecular Formula: C₁₀H₁₃BrN₂O
• Molecular Weight: 257.13
• Product Categories: pharmacetical
• Mol File: 221087-47-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 392.7°Cat760mmHg
• Flash Point: 191.3°C
• Appearance: /
• Density: 1.416g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(6-BROMOPYRIDIN-2-YL)PIVALAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(6-BROMOPYRIDIN-2-YL)PIVALAMIDE(221087-47-4)
• EPA Substance Registry System: N-(6-BROMOPYRIDIN-2-YL)PIVALAMIDE(221087-47-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 221087-47-4(Hazardous Substances Data)

Usage

General Description

N-(6-Bromopyridin-2-yl)pivalamide is a chemical compound that belongs to the family of pyridines, containing an amide group. One of the distinguishing features of this compound is its aromatic ring, which has a bromine atom connected to one of its carbon atoms. Pivalamide — featured in its name — is derived from pivalic acid, indicating the presence of a tertiary carbon atom bonded to an amide group. The exact properties, uses, and safety information for N-(6-Bromopyridin-2-yl)pivalamide are not readily available, implying that it may be used primarily in specialized or research contexts.

InChI:InChI=1/C10H13BrN2O/c1-10(2,3)9(14)13-8-6-4-5-7(11)12-8/h4-6H,1-3H3,(H,12,13,14)

Upstream product

• 19798-81-3 2-Amino-6-bromopyridine 
• 3282-30-2 pivaloyl chloride 
• 144-55-8 sodium hydrogencarbonate 
• 626-05-1 2,6-Dibromopyridine 
• 754-10-9 2,2-dimethylpropionamide 

Downstream Products

• 511277-99-9 2-(4-tert-butyldimethylsilyloxymethyl-5-ethyl-2-methoxy-phenyl)-6-(N-2,2-dimethylpropamido)-pyridine 
• 681171-49-3 N-(6-{4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-5-ethyl-2-methoxy-phenyl}-pyridin-2-yl)-2,2-dimethyl-propionamide 
• 681171-58-4 N-(6-{4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2,5-dimethoxy-phenyl}-pyridin-2-yl)-2,2-dimethyl-propionamide 
• 890049-06-6 C₁₈H₁₈N₂O 
• 613678-03-8 (6-aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone 
• 439239-90-4 Lasmiditan 
• 78177-12-5 6-(1-methylethyl)-2-pyridinamine 
• 1187541-07-6 2,2-dimethyl-N-{6-[1-({[(1-methyl-1H-tetrazol-5-yl)(phenyl)methylene]amino}oxy)ethyl]pyridin-2-yl}propanamide 
• 1187541-00-9 6-[1-({[(1-methyl-1H-tetrazol-5-yl)(phenyl)methylene]amino}oxy)ethyl]pyridin-2-amine 
• 857292-66-1 6-cyclopropyl-2-aminopyridine 
• 1220596-31-5 benzyl 2-(6-pivalamidopyridin-2-yl)ethylcarbamate 
• 852960-68-0 6-(1-naphthylphenylphosphino)-2-pivaloylaminopyridine 
• 890049-05-5 C₂₄H₂₄N₂O 

Relevant articles and documents

2,2-DIMETHYL-N-[6-(1-METHYL-PIPERIDIN-4-CARBONYL)-PYRIDIN-2-YL]-PROPIONAMIDE, METHOD FOR PREPARING (6-AMINO-PYRIDIN-2-YL)-(1-METHYL-PIPERIDIN-4-YL)-METHANONE USING SAID COMPOUND, AND USE OF SAID COMPOUND IN THE PREPARATION OF LASMIDITAN

The present invention relates to a new intermediate, (2,2-dimethyl-N-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-propanamide) useful in the synthesis of lasmiditan, to a method for obtaining same, to the use of said intermediate for preparing lasmiditan, to a method for preparing lasmiditan making use of said intermediate, and to a method for preparing an intermediate ((6-amino-pyridin-2-yl)-(1-methyl-piperidin-4-yl)-methanone) from (2,2-dimethyl-N-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-propanamide).

COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN

The invention relates to compounds, pyridine derivatives, and pharmaceutical 10 compositions containing same for use in the treatment of pain. It also relates to specific compounds, compositions comprising the same and uses thereof, in particular in the treatment of pain.

3-(PYRAZOLYL)-1H-PYRROLO[2,3-b]PYRIDINE DERIVATIVES AS KINASE INHIBITORS

The present application relates to novel 3-(pyrazolyl)-lH-pyrrolo[2,3-b]pyridine derivatives of formula (I), as protein kinase inhibitors. The invention particularly relates to compounds of formula (I), preparation of compounds and pharmaceutical compositions thereof. The invention further relates to pharmaceutically acceptable salts and compositions comprising the said novel 3-(pyrazolyl)-lH-pyrrolo[2,3-b]pyridine derivatives and their use in the treatment of various disorders.