22121-86-4Relevant academic research and scientific papers
HERBICIDAL AND FUNGICIDAL 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLINE-5-THIOAMIDES
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Paragraph 0191; 0192; 0193, (2015/09/28)
Herbicidally and fungicidally active 5-oxy-substituted 3-phenylisoxazoline-5-carboxamides and 5-oxy-substituted 3-phenylisoxazoline-5-thioamides of the formula (I) are described. In this formula (I), X, X2 to X6, R1 to R4 are radicals such as hydrogen, halogen and organic radicals such as substituted alkyl. A is a bond or a divalent unit. Y is a chalcogen.
A tandem "on-palladium" Heck-Jeffery amination route toward the synthesis of functionalized indole-2-carboxylates
McNulty, James,Keskar, Kunal
supporting information; experimental part, p. 6902 - 6908 (2012/01/02)
A direct synthesis of functionalized indole-2-carboxylates involving a PdII-catalyzed annulation of ortho-iodoanilines onto a vinyl ether is described. The reaction mechanism is shown to be distinct from a stepwise Heck, intramolecular amination pathway, likely involving a tandem "on-palladium" Heck-Jeffery amination process incorporating a novel intramolecular amination step.
Intramolecular 4+3 cycloadditions, vinylthionium ions from allylic alcohols
Harmata,Jones
, p. 783 - 786 (2007/10/03)
Aldehyde 9 can be prepared from ethyl pyruvate in several steps. Treatment of 1 with various diene-containing Grignard reagents results in the formation of the corresponding allylic alcohol in good yield. Exposure of these alcohols to triflic anhydride results in the formation of 4+3 cycloadducts in good to excellent yields. Furan and simple butadiene trap the intermediate allylic cation efficiently in the formation of 5,7-fused ring systems. A tethered thiophene undergoes only intramolecular Friedel-Crafts alkylation.
Synthese de la (+/-)-5-Hydroxy-4-Oxo-Norvaline mettant en jeu l'osmylation d'un alcene fonctionnel.
David, Katerine,Cazes, Bernard,Gore, Jacques
, p. 2768 - 2792 (2007/10/03)
The allylation of a glycine equivalent with 2,3-difunctionalized propenes, eventually made in the presence of a Pd(0) complex, leads to compounds the osmylation of which allows in several cases the obtention of (+/-)-5-Hydroxy-4-Oxo-Norvaline in good yield.From a systemic study have emerged the two partners able to produce the target amino-acid in the best conditions.This one was obtained by a three-step sequence from 1,3-dibromopropene and ethyl N-acetamidomalonate with a 75percent overall yield.
