22129-40-4

Upstream product

• 16635-13-5 2'-hydroxy-4-methoxy-5'-methylchalcone 

Downstream Products

• 37689-59-1 2-[5-(4-methoxy-phenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]-4-methyl-phenol 
• 16635-13-5 2'-hydroxy-4-methoxy-5'-methylchalcone 
• 60904-74-7 2-(4-methoxy-benzylidene)-5-methyl-benzofuran-3-one 
• 1032-84-4 (E)-1-(2-hydroxy-5-methylphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 29976-66-7 3'-bromo-2'-hydroxy-4-methoxy-5'-methyl-trans-chalcone 
• 27770-80-5 2-(4-methoxyphenyl)-6-methylchroman-4-one 
• 72149-92-9 3-bromo-4'-methoxy-6-methylflavanone 
• 29976-78-1 8-bromo-4'-methoxy-6-methylflavone 
• 29976-77-0 6-methyl-4'-methoxyflavone 
• 37689-62-6 2-[5-(4-methoxy-phenyl)-1-phenyl-1H-pyrazol-3-yl]-4-methyl-phenol 
• 65840-98-4 3-(2-hydroxy-5-methylphenyl)-5-(4-methoxyphenyl)pyrazole 
• 29976-91-8 3-(2-hydroxy-5-methylphenyl)-5-(4-methoxyphenyl)isoxazole 

Relevant academic research and scientific papers

Ecofriendly bromination of chalcones and synthesis of flavones using grinding technique

Selective bromination of chalcones and 2'-hydroxychalcones has been carried out with ammonium bromide and ammonium persulphate using grinding technique at RT under aqueous moist condition to give α,β-dibromochalcones and α,β-dibromo-2'- hydroxychalcones respectively. α,β- Dibromo-2'-hydroxychalcones have been cyclodehydrobrominated with barium hydroxide moist and ethanol at RT to give flavones using grinding technique.

Synthesis of pyrazole and isoxazole in triethanolamine medium

Reactions of 2′-hydroxy chalcone dibromides 2a-1 with phenyl hydrazine and hydrazine hydrate afford pyrazoles 1a-1 and with hydroxylamine hydrochloride give isoxazoles 5a-f in triethanolamine medium. Similarly reaction of β-diketone 3b-e with phenyl hydra

Bromhydrination of Chalkones in Dimethyl Sulphoxide

A novel method developed for the preparation of α-bromo-β-hydroxychalkones (IIIa-d) involves bromhydrination of the corresponding chalkones (Ia-d) with bromine water in dimethyl sulphoxide at room temperature.