221380-98-9Relevant academic research and scientific papers
Total synthesis of brevetoxin A: Part 3: Construction of GHIJ and BCDE ring systems
Nicolaou,Shi, Guo-Qiang,Gunzner, Janet L.,Gaertner, Peter,Wallace, Paul A.,Ouellette, Michael A.,Shi, Shuhao,Bunnage, Mark E.,Agrios, Konstantinos A.,Veale, Chris A.,Hwang, Chan-Kou,Hutchinson, John,Prasad,Ogilvie, William W.,Yang, Zhen
, p. 628 - 645 (2007/10/03)
Successful syntheses of highly complex intermediates 2 (GHIJ ring system) and 3 (BCDE ring system) for the total synthesis of brevetoxin A (1) are described. Several of our methodologies were utilized to achieve this goal: i) hydroxy epoxide cyclizations
