2217-60-9

Basic information

• Product Name: 2,5-Dihydroxy-p-cymene
• Synonyms: 1,4-Benzenediol, 2-methyl-5- (1-methylethyl)-;THYMOHYDROQUINONE;thymoquinol;2-Isopropyl-5-methyl-1,4-benzenediol;2-Methyl-5-(1-methylethyl)1,4-benzenediol;2-Methyl-5-isopropylbenzene-1,4-diol;2-Methyl-5-isopropylhydroquinone;5-Isopropyl-2-methylhydroquinone
• CAS NO: 2217-60-9
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.22
• Mol File: 2217-60-9.mol
• Article Data: 21

Chemical Properties

• Melting Point: 148°C
• Boiling Point: 290°C (estimate)
• Flash Point: 147.9°C
• Appearance: /
• Density: 1.0060 (rough estimate)
• Vapor Pressure: 0.000427mmHg at 25°C
• Refractive Index: 1.5277 (estimate)
• PKA: 11.11±0.23(Predicted)
• CAS DataBase Reference: 2,5-Dihydroxy-p-cymene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dihydroxy-p-cymene(2217-60-9)
• EPA Substance Registry System: 2,5-Dihydroxy-p-cymene(2217-60-9)

Safety Data

• Hazardous Substances Data: 2217-60-9(Hazardous Substances Data)

Usage

Description

2,5-Dihydroxy-p-cymene, a member of the p-menthane class of organic compounds, is a derivative of cymene, a naturally occurring aromatic hydrocarbon. 2,5-Dihydroxy-p-cymene is distinguished by the presence of two hydroxyl groups at the 2 and 5 positions on the cymene molecule. Recognized for its antioxidant and antimicrobial properties, 2,5-Dihydroxy-p-cymene has emerged as a potential bioactive compound with applications in various fields, including pharmaceuticals and as a natural preservative in food products. Its anti-inflammatory and analgesic properties further position it as a promising candidate for the development of innovative therapeutic agents.

Uses

Used in Pharmaceutical Industry:
2,5-Dihydroxy-p-cymene is used as a bioactive compound for its potential therapeutic applications due to its antioxidant, antimicrobial, anti-inflammatory, and analgesic properties. It is being studied for its potential to contribute to the development of novel pharmaceutical agents that can address various health conditions.
Used in Food Preservation:
2,5-Dihydroxy-p-cymene is used as a natural preservative in food products to extend their shelf life and maintain freshness. Its antimicrobial properties help inhibit the growth of spoilage-causing microorganisms, ensuring the safety and quality of food items.
Used in Antimicrobial Applications:
In the field of antimicrobial research, 2,5-Dihydroxy-p-cymene is utilized as an active ingredient to combat microbial infections. Its ability to inhibit the growth of bacteria and other microorganisms makes it a valuable asset in the development of new antimicrobial treatments and preventive measures.
Used in Antioxidant Formulations:
2,5-Dihydroxy-p-cymene is used as an antioxidant in various formulations to protect against oxidative stress and related cellular damage. Its antioxidant properties can be harnessed in the development of health supplements, skincare products, and other applications where protection from free radicals is essential.
Used in Anti-inflammatory and Analgesic Agents:
2,5-Dihydroxy-p-cymene is used as an ingredient in anti-inflammatory and analgesic agents due to its inherent properties to reduce inflammation and alleviate pain. This makes it a potential component in medications and topical treatments for conditions characterized by inflammation and pain.

InChI:InChI=1/C10H14O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6,11-12H,1-3H3

Upstream product

• 1128-28-5 4-aminothymol 
• 14753-08-3 2,5-dimethoxy-p-cymene 
• 490-91-5 thymoquinone 
• 7803-49-8 hydroxylamine 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 
• 29096-93-3 dibromothymoquinone 
• 67-64-1 acetone 
• 89-83-8 thymol 
• 7664-93-9 sulfuric acid 
• 4221-98-1 (R)-5-isopropyl-2-methylcyclohexa-1,3-diene 
• 1740-97-2 2-methyl-4-isopropylphenol 
• 2364-54-7 4-nitrosothymol 
• 95645-53-7 6-hydroxythymol 3-O-β-D-glucopyranoside 

Downstream Products

• 112867-80-8 2-isopropyl-5-methyl-[1,4]benzoquinone; compound with 2-isopropyl-5-methyl-hydroquinone 
• 96447-67-5 4-methoxycarvacrol 
• 10012-48-3 p-methoxythymol 
• 14753-08-3 2,5-dimethoxy-p-cymene 
• 610-92-4 2,5-dihydroxy-1,4-benzenedicarboxylic acid 
• 38618-26-7 p-menthane-2,5-diol 
• 6307-97-7 3-bromo-5-isopropyl-2-methylcyclohexa-2,5-diene-1,4-dione 
• 29096-93-3 dibromothymoquinone 
• 490-91-5 thymoquinone 
• 104097-45-2 2,5-dihydroxy-3-isopropyl-6-methyl-benzaldehyde 
• 700799-32-2 1-isopropyl-4-methyl-2,5-bis-(2-piperidino-ethoxy)-benzene 
• 102273-95-0 2-hydroxythymol diacetate 
• 121759-20-4 1-isopropyl-4-methyl-2,5-bis-[2-(1-methyl-piperidinium-1-yl)-ethoxy]-benzene; diiodide 
• 69203-13-0 2,5-dibromo-3-methyl-6-isopropylhydroquinone 

Relevant articles and documents

New broth macrodilution volatilization method for antibacterial susceptibility testing of volatile agents and evaluation of their toxicity using modified mtt assay in vitro

In this study, a new broth macrodilution volatilization method for the simple and rapid determination of the antibacterial effect of volatile agents simultaneously in the liquid and vapor phase was designed with the aim to assess their therapeutic potenti

In vitro potential antiviral SARS-CoV-19- activity of natural product thymohydroquinone and dithymoquinone from Nigella sativa

Inflammation, oxidation, and compromised immunity all increase the dangers of COVID-19, whereas many pharmaceutical protocols may lead to increased immunity such as ingesting from sources containing vitamin E and zinc. A global search for natural remedies

Synthesis of Novel Bivalent Hydrazino-Thymohydroquinone Analogs Derived from Thymoquinone as Potential Antimicrobial Agents

In our previous work, it was reported that thymoquinone (TQ) and some thymohydroquinone (THQ) derivatives were used as precursors for the synthesis of potential anticancer agents. Hence, as a part of our ongoing program in the design of biologically activ