22185-75-7

Usage

Uses

Used in Chemical Synthesis:
N-[3-(Diethylamino)phenyl]propionamide is used as a reactant in chemical reactions for the synthesis of more complex molecules. Its role as an amide allows it to participate in various organic chemistry processes, potentially leading to the creation of new compounds with diverse applications.
Used in Pharmaceutical Development:
Although the safety, toxicity, and environmental impact of N-[3-(Diethylamino)phenyl]propionamide are not sufficiently documented, its structural characteristics suggest that it could potentially be used in the development of pharmaceuticals. As with other similar molecules, it may contribute to the formulation of new drugs or serve as an intermediate in the synthesis of active pharmaceutical ingredients.
Used in Polymer Manufacturing:
N-[3-(Diethylamino)phenyl]propionamide may also be used in the manufacturing of polymers. Its amide functionality could be incorporated into polymer structures, potentially influencing their properties and performance. This could be particularly relevant in industries where specific material characteristics are required, such as in the production of plastics, coatings, or adhesives.

InChI:InChI=1/C13H20N2O/c1-4-13(16)14-11-8-7-9-12(10-11)15(5-2)6-3/h7-10H,4-6H2,1-3H3,(H,14,16)

Upstream product

• 26513-20-2 N,N-diethyl-1,3-benzenediamine 
• 123-62-6 propionic acid anhydride 
• 64-67-5 diethyl sulfate 
• 99-09-2 3-nitro-aniline 
• 2216-16-2 N,N-diethyl-3-nitroaniline 
• 108-45-2 m-phenylenediamine 
• 7470-50-0 N-(3-nitrophenyl)propionamide 
• 22987-10-6 1-amino-3-propionylamino-benzene 

Downstream Products

• 56935-81-0 N-[2-(2-Bromo-4,6-dinitro-phenylazo)-5-diethylamino-phenyl]-propionamide 
• 56968-03-7 N-[2-(2-Cyano-4,6-dinitro-phenylazo)-5-diethylamino-phenyl]-propionamide 
• 94510-18-6 N-[2-(2,6-Dicyano-4-nitro-phenylazo)-5-diethylamino-phenyl]-propionamide 
• 85929-33-5 (E)-N-(2-((2-bromo-6-cyano-4-nitrophenyl)diazenyl)-5-(diethylamino)phenyl)propionamide 

Relevant academic research and scientific papers

Synthesis and NMR-spectral characterization of N,N-dialkyl-3-nitroanilines, N,N-dialkyl-1,3-benzenediamines and their acyl derivatives

A recently discovered method for the synthesis of N,N-dialkyl-1,3-benzenediamines with two different alkyl groups is shown to be general.This is demonstrated by the synthesis of N-butyl-N-phenethyl-1,3-benzenediamine by the condensation of 3-nitroaniline with phenylacetaldehyde and benzotriazole, reduction of the adduct with sodium borohydride, acylation of the resulting N-phenethyl-3-nitroaniline with butyryl chloride, catalytic reduction of the nitro group by formic acid in the presence of triethylamine and palladium and finally reduction of the butyramide carbonyl group to the butyl substituent by lithium aluminium hydride.Several other routes were less efficient or failed completely.Classical methods for the synthesis of N,N-diethyl-1,3-benzenediamine were reexamined and improved.The recommended procedure involves alkylation of 3-nitroaniline with diethyl sulfate, trapping of N-ethyl-3-nitroaniline (by-product) by benzoylation, distillation of N,N-diethyl-3-nitro-aniline under reduced pressure and reduction of the nitro group by formic acid catalyzed by palladium.

Synthesis and Spectral Characterization of Blue Dyes of the Benzene Series

53 Donor-acceptor substituted azo dyes of the benzene series were prepared by diazonium-coupling reactions (1a-s) or halogen-cyanide exchange (->2a-x, 3a-j).Described are the preparation of the amines 4a-m and the coupling compounds 5a-t and the procedure of diazotizing and coupling.The colouristic and spectroscopic data show that compounds of the general formula 1 are excellent brilliant blue azo dyes usefull for dyeing polyester material.

Rubine disazo acid dyes for polyamides

Dyes of the formula STR1 wherein B and D are each independently 1,4-phenylene or 1,4-naphthylene; M is hydrogen, lithium, sodium, potassium or ammonium; A1 is hydrogen, C1-4 alkoxy, C1-4 alkyl, trifluoromethyl, nitro, chloro, bromo, cyano, or hydroxy; B1 and B2 are each hydrogen, C1-3 alkoxy, C1-3 alkyl, chloro or bromo; D1 is hydrogen, C1-4 alkoxy, C1-4 alkyl, or chloro; D2 is hydrogen, C1-4 alkoxy, C1-4 alkyl, chloro, bromo, fluoro, or acylamino, acyl being C1-5 alkanoyl, C1-5 alkylsulfonyl, benzoyl or benzenesulfonyl, each acyl unsubstituted or substituted with 1 to 3 of C1-2 alkyl, C1-2 alkoxy, chloro, bromo, cyano, or hydroxy; and R1 and R2 are each C1-6 alkyl, C1-6 chloro or bromoalkyl, C2-6 hydroxy- or dihydroxyalkyl, C2-6 alkoxyalkyl, C1-6 cyanoalkyl, or phenyl-C1-2 alkyl (phenyl unsubstituted or substituted with 1 to 3 of C1-2 alkyl, C1-2 alkoxy, chloro, bromo, cyano or hydroxy) are useful in dyeing natural and synthetic polyamide fibers in deep and level shades of red to blue.