222408-90-4

Usage

Uses

Used in Agricultural Fungicides:
2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2,4-triazolidine-3-thione is used as an active ingredient in agricultural fungicides. Its antifungal properties help protect crops from various fungal infections, ensuring higher yields and better quality produce.
Used in Herbicides:
In addition to its fungicidal properties, 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2,4-triazolidine-3-thione is also used in herbicides. It helps control the growth of unwanted plants and weeds, allowing for more efficient cultivation and management of agricultural fields.

Upstream product

• 222408-91-5 [2-(1-chloro-cycloprop-1-yl)-3-(2-chlorophenyl)-2-hydroxy]-propyl-1-hydrazine 
• 50-00-0 formaldehyd 
• 540-72-7 sodium thiocyanide 
• 463-56-9 thiocyanic acid 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 120983-72-4 1-chlorocyclopropyl-2-chloro-ethan-1-one 
• 611-19-8 1-chloro-2-(chloromethyl)benzene 
• 1147550-11-5 ammonium thiocyanate 
• 139297-65-7 1-(1-chlorocyclopropyl)-2-(2-chlorophenyl)ethanone 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 303048-98-8 prothioconazole 
• 178928-70-6 2?[(2RS)?2?(1?chlorocyclopropyl)?3?(2?chlorophenyl)?2?hydroxypropyl]?2H?1,2,4?triazole?3(4H)?thione 

Relevant academic research and scientific papers

Preparation method of prothioconazole compound

The invention relates to the field of bactericides, and discloses a preparation method of a prothioconazole compound. The method comprises the steps of 1) reacting a compound with a structure as shown in a formula (1) defined in the description with hydra

Preparation method of prothioconazole intermediate

The invention relates to a preparation method of a prothioconazole intermediate. In order to solve the problem that the existing prothioconazole intermediate 2 - (1 - chlorocyclopropyl) -1 - (2 - chlorophenyl) -3 - hydrazinopropane -2 - alcohol synthesis

AN INDUSTRIAL SCALE PROCESS FOR THE PREPARATION OF PROTHIOCONAZOLE

The present invention relates to an industrial scale process for the preparation of Prothioconazole (I), which is simple, economical, efficient, user and environment friendly, moreover commercially viable with higher yield and greater chemical purity.

Synthetic method of prothioconazole intermediate

The invention provides a synthetic method of a prothioconazole intermediate. According to the invention, an acid catalyst or a composite acid catalyst is used for catalyzing a reaction, so that the reaction rate and the yield are increased, the problem of high salt content in materials and wastewater in the step is solved; and the synthesis method has the advantages of simple operation, less wastewater, small salt content in intermediates and wastewater, short reaction time, mild conditions, yield of more than or equal to 90% and purity of more than or equal to 97%.

Preparation method of prothioconazole intermediate

The invention provides a preparation method of a prothioconazole intermediate. The method comprises the following steps: (1) dissolving a compound (I) serving as a substrate in methanol, dropwise adding a formaldehyde aqueous solution, dropwise adding thi

Method for continuously producing prothioconazole by using microchannel reactor and microchannel system (by machine translation)

In the microchannel reactor, 2 - (1 - chlorocyclopropyl) -1 - (2 - chlorophenyl) -3 - hydrazine-propan -2 - alcohol is used as a raw material to continuously complete the preparation process of propiconazole through a cyclization and oxidation two-step re

IMPROVED AND EFFICIENT PROCESS FOR THE SYNTHESIS OF 2-[2-(1-CHLOROCYCLOPROPYL)-3-(2-CHLOROPHENYL)-2- HYDROXYPROPYL]-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE (PROTHIOCONAZOLE) AND ITS INTERMEDIATES

The present invention relates to an improved and efficient process for the synthesis of 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4- triazole-3-thione, compound of formula (I) (Prothioconazole). The present inventio

Preparation method of prothioconazole

The invention provides a preparation method of prothioconazole. The preparation method comprises steps as follows: A), a compound represented as formula I is subjected to a chlorination cyclization reaction, and a compound represented as formula II is obt

Triazoline thione compound preparation method

The present invention relates to the field of preparation and control of diseases of crops, and discloses a triazoline thione compound preparation method, which comprises: carrying out a reaction on atriazolidine thione compound represented by a formula (