2226-36-0Relevant academic research and scientific papers
Rapid Syntheses of [11C]Arylvinyltrifluoromethanes through Treatment of (E)-Arylvinyl(phenyl)iodonium Tosylates with [11C]Trifluoromethylcopper(I)
Jana, Susovan,Telu, Sanjay,Yang, Bo Yeun,Haskali, Mohammad B.,Jakobsson, Jimmy E.,Pike, Victor W.
supporting information, p. 4574 - 4578 (2020/06/05)
We report a method for labeling arylvinyltrifluoromethanes with carbon-11 (t1/2 = 20.4 min) as representatives of a new radiolabeled chemotype that has potential for developing radiotracers for biomedical imaging with positron emission tomography. Treatme
Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent
Wang, Xiao-Ping,Lin, Jin-Hong,Zhang, Cheng-Pan,Xiao, Ji-Chang,Zheng, Xing
supporting information, p. 2635 - 2640 (2014/01/06)
An efficient method for the copper-catalyzed trifluoromethylation of terminal alkenes with an electrophilic trifluoromethylating reagent has been developed. The reactions proceeded smoothly to give trifluoromethylated alkenes in good to excellent yields. The results provided a versatile approach for the construction of Cvinyl-CF3 bonds without using prefunctionalized substrates.
