460-37-7

Basic information

• Product Name: 1-IODO-3,3,3-TRIFLUOROPROPANE
• Synonyms: 3-IODO-1,1,1-TRIFLUOROPROPANE;1-IODO-3,3,3-TRIFLUOROPROPANE;1-IODO-2-(PERFLUOROALKYL)ETHANE;3,3,3-TRIFLUOROPROPYL IODIDE;1,1,1-TRIFLUORO-3-IODOPROPANE;1-Iodo-3,3,3-trifluoropropane 98%;1-Iodo-3,3,3-trifluoropropane98%;1,1,1-Trifluoro-3-iodopropane, 98+%
• CAS NO: 460-37-7
• Molecular Formula: C₃H₄F₃I
• Molecular Weight: 223.96
• EINECS: 1592732-453-0
• Product Categories: Alkyl;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 460-37-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 80 °C(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless to pink/Liquid
• Density: 1.911 g/mL at 25 °C(lit.)
• Vapor Pressure: 64.9mmHg at 25°C
• Refractive Index: n20/D 1.42(lit.)
• Storage Temp.: 2-8°C(protect from light)
• Sensitive: Light Sensitive
• BRN: 1698182
• CAS DataBase Reference: 1-IODO-3,3,3-TRIFLUOROPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-IODO-3,3,3-TRIFLUOROPROPANE(460-37-7)
• EPA Substance Registry System: 1-IODO-3,3,3-TRIFLUOROPROPANE(460-37-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 460-37-7(Hazardous Substances Data)

Usage

Chemical Properties

Clear colorless to pink liquid

InChI:InChI=1/C3H4F3I/c4-3(5,6)1-2-7/h1-2H2

Synthetic route

ethene (74-85-1) + iodotrifluoromethane (2314-97-8) → 1,1,1-trifluoro-3-iodopropane (460-37-7)

Conditions	Yield
Irradiation.mit UV-Licht;
at 200 - 250℃;
With mercury at 200 - 250℃;
at 275℃;
at 200℃; for 37h;

3-bromo-1,1,1-trifluoropropane (460-32-2) → 1,1,1-trifluoro-3-iodopropane (460-37-7)

Conditions	Yield
With acetone; sodium iodide

3-iodopropanoic acid (141-76-4) → 1,1,1-trifluoro-3-iodopropane (460-37-7) + bis-(3-iodo-1,1-difluoro-propyl) ether (51100-36-8)

Conditions	Yield
With sulfur tetrafluoride at 23℃; for 20h;

1-methylbuta-1,3-diene (2004-70-8) + ethene (74-85-1) + iodotrifluoromethane (2314-97-8) → Z-piperylene (1574-41-0) + 1,1,1-trifluoro-3-iodopropane (460-37-7) + deca-1,3,7,9-tetraene (32509-35-6) + 1,1,1-trifluorohex-3-ene (53392-88-4)

Conditions	Yield
at 130℃; for 2.3h; Irradiation; Title compound not separated from byproducts;

ethene (74-85-1) + iodotrifluoromethane (2314-97-8) → 1,1,1-trifluoro-3-iodopropane (460-37-7) + vinyliodide (593-66-8) + 1,1,1-trifluoropropylene (677-21-4) + acetylene (74-86-2)

Conditions	Yield
under 820 Torr; Quantum yield; Irradiation; CO2 laser induced telomerization;

ethene (74-85-1) + iodotrifluoromethane (2314-97-8) → 1,1,1-trifluoro-3-iodopropane (460-37-7) + 1,1,1-trifluoropropane (421-07-8) + 1,1,1-trifluoro-5-iodopentane (352-60-3)

Conditions	Yield
je nach den Bedingungen;

ethene (74-85-1) + iodotrifluoromethane (2314-97-8) + mercury → 1,1,1-trifluoro-3-iodopropane (460-37-7) + 1,1,1-trifluoropropane (421-07-8) + 1,1,1-trifluoro-5-iodopentane (352-60-3) + 3.3.3-trifluoro-propylmercury iodide

Conditions	Yield
je nach den Bedingungen;

Upstream product

• 74-85-1 ethene 
• 2314-97-8 iodotrifluoromethane 
• 2004-70-8 1-methylbuta-1,3-diene 
• 141-76-4 3-iodopropanoic acid 
• 460-32-2 3-bromo-1,1,1-trifluoropropane 

Downstream Products

• 460-35-5 3-chloro-1,1,1-trifluoropropane 
• 677-21-4 1,1,1-trifluoropropylene 
• 2342-67-8 3,3,3-trifluoropropyl-4-methylbenzene sulphonate 
• 371-26-6 ethyl 4,4,4-trifluorobutanoate 
• 406-93-9 4,4,4-trifluorobutyric acid 
• 30320-28-6 1,1,1,2,2,3,3,5,5,5-decafluoro-4-trifluoromethyl-pentane 
• 359-72-8 perfluoro-2-methylpent-1-ene 
• 406-82-6 1,1,1-trifluoropentane 
• 3834-39-7 1,1,1,6,6,6-hexafluorohexane 
• 106-97-8 n-butane 
• 110-54-3 hexane 
• 17337-12-1 1-(trifluoromethyl)pentane 
• 713-02-0 1-phenyl-4,4,4-trifluoro-1-butanone 
• 1579-80-2 (3,3,3-trifluoropropyl)benzene 

Relevant articles and documents

THE REACTIONS OF TRIFLUOROMETHYL AND TRICHLOROMETHYL RADICALS WITH CONJUGATED AND METHYLENE-INTERRUPTED DIENES AND ENYNES

The photochemical addition of CF3I to buta-1,3-diene and vinylacetylene in the gas phase gave 1,4-adducts as the main products.In gas phase reactions only products derived from hydrogen abstraction were detected in the CF3I penta-1,3-diene system, but the 1,4-adducts again predominated in the liquid phase.CCl3Br similarly gave a mixture of 1,2- and 1,4-adducts, the latter predominating, on photochemical reaction with penta-1,3-diene.The 1,2-adduct was the main product from the CCl3Br/pent-1-en-4-yn reaction, but some hydrogen abstraction was observed.The preference shown by conjugated dienes to give 1,4-adducts in the trans- configuration is interpreted in terms of steric factors and the propensity of dienes to adopt the s-trans conformation.