22297-05-8Relevant articles and documents
Carboxylate-Directed Addition of Aromatic C-H Bond to Aromatic Aldehydes under Ruthenium Catalysis
Miura, Hiroki,Terajima, Sachie,Shishido, Tetsuya
, p. 6246 - 6254 (2018)
We report that ruthenium complexes effectively catalyzed the carboxylate-directed addition of aromatic C-H bonds to aldehydes. The reactions of aromatic acids with a variety of aromatic aldehydes including unactivated ones proceeded efficiently to give the corresponding isobenzofuranone derivatives in high yields. The combination of ruthenium(II) complexes with tricyclohexylphosphine led to highly nucleophilic aryl-metal species, which enabled versatile [3 + 2] cycloaddition in the absence of a Lewis acid. This paper also demonstrates the application of supported ruthenium catalysts to the title reaction.
Synthesis of 3-Unsubstituted Phthalides from Aryl Amides and Paraformaldehyde via Ruthenium(II)-Catalyzed C–H Activation
Zhou, Chao,Zhao, Junqi,Chen, Wenkun,Imerhasan, Mukhtar,Wang, Jun
supporting information, p. 6485 - 6488 (2020/10/02)
A straightforward and convenient route has been developed for the synthesis of 3-unsubstituted phthalide derivatives from aryl amides and paraformaldehyde by ruthenium(II)-catalyzed C–H activation. The reaction proceeds through tandem ortho-hydroxymethylation of aryl amide and subsequent intramolecular lactonization.
Synthesis of isoindoles by one-electron reductions of dibenzo[1,4]diazocines
Bovenkerk, Marcel,Esser, Birgit
, p. 775 - 785 (2015/01/30)
A synthetic protocol to isoindoles is reported through one-electron reductions of dibenzo[1,4]diazocines. The utility of the approach has been demonstrated through the synthesis of six novel isoindole derivatives. Photophysical measurements revealed emissions between 440 and 460 nm. A reaction mechanism, supported by experimental results and quantum chemical calculations, is postulated.
