223591-26-2

Usage

General Description

1,3-Benzenediol,5-[6-hydroxy-2-(4-hydroxyphenyl)-4-[(1E)-2-(4-hydroxyphenyl)ethenyl]-3-benzofuranyl]- is a complex chemical compound with antioxidant and anti-inflammatory properties. Also known as resveratrol, it is found in various plant species, including grapes, peanuts, and berries. Studies have shown that resveratrol may have potential health benefits, such as reducing the risk of heart disease, cancer, and age-related cognitive decline. It is also being investigated for its potential in skincare and anti-aging products due to its ability to protect against environmental stressors and promote skin health. However, further research is needed to fully understand the potential benefits and risks of 1,3-Benzenediol,5-[6-hydroxy-2-(4-hydroxyphenyl)-4-[(1E)-2-(4-hydroxyphenyl)ethenyl]-3-benzofuranyl]-.

Upstream product

• 223558-50-7 trans-ε-viniferin pentaacetate 
• 19520-74-2 3-hydroxy-5-methoxy-benzoic acid methyl ester 
• 50841-50-4 (2-bromo-1-(3,5-dimethoxyphenyl)ethanone) 
• 2628-17-3 4-Vinylphenol 
• 1180491-77-3 methyl 3-(2-(3,5-dimethoxyphenyl)-2-oxoethoxy)-5-methoxybenzoate 
• 1180491-75-1 methyl 3-(3,5-dimethoxyphenyl)-6-methoxybenzofuran-4-carboxylate 
• 62218-08-0 trans-ε-viniferin 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 1145-93-3 diethyl 4-methoxybenzylphosphonate 
• 128962-14-1 (E)-3-(3,5-Dimethoxyphenyl)-6-methoxy-2-(4-methoxyphenyl)-4-<2-(4-methoxyphenyl)ethenyl>benzofuran 

Downstream Products

• 128962-14-1 (E)-3-(3,5-Dimethoxyphenyl)-6-methoxy-2-(4-methoxyphenyl)-4-<2-(4-methoxyphenyl)ethenyl>benzofuran 

Relevant academic research and scientific papers

Total Synthesis of Viniferifuran, Resveratrol-Piceatannol Hybrid, Anigopreissin A and Analogues – Investigation of Demethylation Strategies

Resveratrol-based natural products constitute a valuable source of unique compounds with diverse biological activities. In this report we investigate demethylation strategies to minimize formation of cyclized and dimerized products during the synthesis of viniferifuran and analogues. We found that boron trichloride/tetra-n-butylammonium iodide (BCl3/TBAI) is typically more effective than boron tribromide (BBr3). Based on these findings we carried out the first syntheses of dehydro-δ-viniferin, resveratrol-piceatannol hybrid and anigopreissin A. In addition, we have developed a short and efficient route to viniferifuran that was obtained in 13% yield over six steps. (Figure presented.).

New oligostilbenes having a benzofuran from Vitis vinifera 'Kyohou'

Three new oligostilbenes having a benzofuran moiety, viniferifuran, (+)- vitisifuran A and (-)-vitisifuran B, were isolated from Vitis vinifera 'Kyohou'. The structures of these oligostilbenes including the absolute configuration were elucidated by spectroscopic and chemical methods. Furthermore, these were chemically transformed from (+)-ε-viniferin, (+)- vitisin A and (-)-vitisin B, respectively, whose absolute configurations are known.