22426-89-7

Basic information

• Product Name: Benzamide, 4-methoxy-N-(phenylmethoxy)-
• CAS NO: 22426-89-7
• Molecular Formula: C15H15NO3
• Molecular Weight: 257.289
• Mol File: 22426-89-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-methoxy-N-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-methoxy-N-(phenylmethoxy)-(22426-89-7)
• EPA Substance Registry System: Benzamide, 4-methoxy-N-(phenylmethoxy)-(22426-89-7)

Safety Data

• Hazardous Substances Data: 22426-89-7(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 57139-22-7 potassium p-methoxylbenzohydroxamate 
• 622-33-3 N-benzyloxyamine 
• 100-07-2 4-methoxy-benzoyl chloride 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 155164-68-4 4,5-Dichloro-2-(4-methoxy-benzoyl)-2H-pyridazin-3-one 
• 121-98-2 methyl 4-methoxybenzoate 
• 100-09-4 4-methoxybenzoic acid 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 63539-58-2 O-Benzoylsulfonyl-N-benzyloxy-p-anisimidsaeure 
• 137042-73-0 C₁₅H₁₄BrNO₂ 
• 281668-91-5 N-benzyloxy-N-(4-bromobenzyl)-4-methoxy-benzamide 
• 281668-93-7 N-(4-bromobenzyl)-4-methoxy-benzamide 
• 6316-54-7 4-methoxy-benzoic acid benzyl ester 
• 874-90-8 4-methoxybenzonitrile 

Relevant articles and documents

Photochemical Activation of Aromatic Aldehydes: Synthesis of Amides, Hydroxamic Acids and Esters

A cheap, facile and metal-free photochemical protocol for the activation of aromatic aldehydes has been developed. Utilizing thioxanthen-9-one as the photocatalyst and cheap household lamps as the light source, a variety of aromatic aldehydes have been activated and subsequently converted in a one-pot reaction into amides, hydroxamic acids and esters in good to high yields. The applicability of this method was highlighted in the synthesis of Moclobemide, a drug against depression and social anxiety. Extended and detailed mechanistic studies have been conducted, in order to determine a plausible mechanism for the reaction.

Palladium-Nanoparticles-Catalyzed Oxidative Annulation of Benzamides with Alkynes for the Synthesis of Isoquinolones

A novel method to synthesize isoquinolones via oxidative annulation of N-alkoxy benzamides and alkynes using binaphthyl-stabilized palladium nanoparticles (Pd-BNP) as catalyst has been developed. This methodology affords various isoquinolone derivatives in good to excellent yields with high regioselectivities in the presence of air as oxidant. N-Methoxybenzothioamide was also found to undergo oxidative annulation with alkyne successfully and provided a sulfur analogue of isoquinolones in moderate yields. The Pd-BNP catalyst was easily recovered and reused up to four times without any apparent agglomeration. (Figure presented.).

N-[(diphenoxyphosphoryl)oxy]-2-phenyl-1H-benzimidazole as a versatile reagent for synthesis O-alkylhydroxamic acids

(Chemical Equation Presented) Highly efficient reagent, N-[(diphenoxyphosphoryl)oxy]-2-phenyl-1H-benzimidazole was synthesized and its applicability was demonstrated for the synthesis of O-alkyl hydroxamic acids. The efficiency of the reagent was evaluate