2251-81-2

Basic information

• Product Name: 1,2,3,4,5-Pentafluoro-6-ethylbenzene
• Synonyms: 1,2,3,4,5-Pentafluoro-6-ethylbenzene;1-Ethyl-2,3,4,5,6-pentafluorobenzene
• CAS NO: 2251-81-2
• Molecular Formula: C₈H₅F₅
• Molecular Weight: 0
• Mol File: 2251-81-2.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3,4,5-Pentafluoro-6-ethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4,5-Pentafluoro-6-ethylbenzene(2251-81-2)
• EPA Substance Registry System: 1,2,3,4,5-Pentafluoro-6-ethylbenzene(2251-81-2)

Safety Data

• Hazardous Substances Data: 2251-81-2(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 653-34-9 2,3,4,5,6-pentafluorostyrene 
• 201230-82-2 carbon monoxide 
• 617-86-7 triethylsilane 
• 652-29-9 2',3',4',5',6'-pentafluoroacetophenone 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 1231760-55-6 [Rh{B(pinacolato)₂}(PEt₃)₃] 
• 75070-85-8 rhodium hydrido (PEt₃)3 complex 
• 74-85-1 ethene 
• 363-72-4 Pentafluorobenzene 
• 392-56-3 Hexafluorobenzene 
• 925-90-6 ethylmagnesium bromide 
• 215500-01-9 pentafluorophenylxenonium(II) tetrafluoroborate 
• 2206-26-0 [D₃]acetonitrile 

Downstream Products

• 52223-81-1 4-Ethyl-2,3,5,6-tetrafluorphenol 

Relevant articles and documents

C-H and C-F bond activation reactions of pentafluorostyrene at rhodium complexes

The rhodium(i) complexes [Rh(Bpin)(PEt3)3] (1), [Rh(H)(PEt3)3] (5) and [Rh(Me)(PEt3)3] (14) were employed in reactions with pentafluorostyrene affording coordination of the olefin and C-F o

Remarkable Dependency of Regioselectivity on the Catalyst Metal Species in the Hydroformylation of Trifluoropropene and Pentafluorostyrene

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+: A Masked Potent Boron Lewis Acid

The chemistry of the boron cation has been revitalized in the past decade due to its newfound application in stoichiometric and catalytic organic reactions. To extend the frontier of boron cation catalysis, we came to discover that a mesityl-substituted η5-Cp*-coordinated boron cation could serve as a powerful Lewis acid for organic catalytic transformations. The boron cation [Cp*B-Mes][B(C6F5)4] ([1][B(C6F5)4]) stabilized in a boronium-like electronic structure binds to Et3PO readily and displays an acceptor number exceeding that of B(C6F5)3 on the Gutmann-Beckett acidity scale. The steric and electronic stabilization exerted by the electron-donating Cp? renders the highly Lewis acidic boron cation an easy-to-handle catalyst for hydrodeoxygenation of aryl ketones at ambient temperature. The exceptional catalytic performance of [1]+ implies that the incorporation of a coordinatively flexible substituent at boron is critical in bringing catalytic activity and stability to boron cation catalysts.

Phosphido- and Amidozirconocene Cation-Based Frustrated Lewis Pair Chemistry

Methyl abstraction from neutral [Cp2ZrMe(ERR)] complexes 1 (E = N, P; R, R'; = alkyl, aryl) with either B(C6F5)3 or [Ph3C][B(C6F5)4] results in the formation of [Cp2Zr(ERR′)][X] complexes 2 (X- = MeB(C6F5)3-, B(C6F5)4-). The X-ray structure of amido complexes [Cp2Zr(NPh2)][MeB(C6F5)3] (2d) and [Cp2Zr(NtBuAr)][B(C6F5)4] (2e′, Ar = 3,5-C6H3(CH3)2) is reported, showing a sterically dependent Zr/N' interaction. Complexes 2 catalyze the hydrogenation of electron-rich olefins and alkynes under mild conditions (room temperature, 1.5 bar H2). Complex 2e binds CO2, giving [Cp2Zr(CO2)(NtBuAr)]2[MeB(C6F5)3]2 (3e). Amido complex 2d reacts with benzaldehyde yielding [Cp2Zr(OCH2Ph)((OC)PhNPh2)][MeB(C6F5)3] (7d). Phosphido complex [Cp2Zr(PCy2)][MeB(C6F5)3] (2a) reacts with diphenylacetylene to yield frustrated Lewis pair [Cp2Zr(PhCCPh)(PCy2)][MeB(C6F5)3] (8a) which further reacts with a range of carbonyl substrates.