22585-81-5

Upstream product

• 1005-33-0 4-chlorophenyldichlorophosphine 
• 31199-91-4 tetrachloro-(4-chloro-phenyl)-phosphorane 
• 106-39-8 bromochlorobenzene 
• 1005-34-1 p-chlorophenylphosphonous acid 
• 108-90-7 chlorobenzene 
• 75-44-5 phosgene 
• 13114-07-3 dimethyl (4-chlorophenyl)phosphonate 
• 5431-35-6 4-chlorophenylphosphonic acid 

Downstream Products

• 7252-93-9 bis-aziridin-1-yl-(4-chloro-phenyl)-phosphine oxide 
• 1535-37-1 (4-chloro-phenyl)-phosphonic acid-difluoride 
• 5431-35-6 4-chlorophenylphosphonic acid 
• 147137-80-2 2-(4-Chlorophenyl)-1,3-dihydro-5,6-dimethyl-1,3,2-benzodiazaphosphol-2-oxid 
• 147137-75-5 2-(4-Chlorophenyl)-1,3-dihydro-5-nitro-1,3,2-benzodiazaphosphol-2-oxid 
• 68694-38-2 Pinacol-p-chlorophenyl-phosphonat 
• 78-50-2 cyanex-921 
• 1005-33-0 4-chlorophenyldichlorophosphine 
• 840506-40-3 (2S)-benzyl 2-(((RS)-chloro(4-chlorophenoxy)phosphoryl)amino)propanoate 
• 97730-56-8 (4-chloro-3-nitro-phenyl)-phosphonic acid 

Relevant academic research and scientific papers

Reactions of aryltetrachlorophosphoranes with sodium dithionite and sulfuryl chloride

Reaction of aryltetrachlorophosphoranes with sodium dithionite or sulfuryl chloride leads to dichloroanhydrides of arylphosphonic acids in high yields. 1996 MAEe cyrillic signK Hayκa/Interperiodica Publishing.

DIARYLPHOSPHINIC AZIDES. PHOTOCHEMICAL REACTIONS INCLUDING REARRANGEMENT IN METHANOL

On photolysis in methanol the diarylphosphinic azides Ar2P(O)N3 (Ar=phenyl, p-tolyl, p-anisyl, p-chlorophenyl) rearrange with loss of nitrogen to form (monomeric) metaphosphonimidates which are trapped by the solvent to give methyl NP-diarylphosphonamidates (7) (41-53percent).Diarylphosphinic amides (18-42percent) are also usually formed, presumably from (triplet) nitrenes.The limited evidence available suggests that the rearrangements take place directly from the photo-excited azides rather than via (singlet) nitrene intermediates.One of the products of rearrangement, methyl NP-di(p-chlorophenyl)phosphonamidate, suffers extensive photochemical dechlorination giving methyl N-phenyl-P-p-chlorophenylphosphonamidate.

SYNTHESIS OF PHOSPHONIC DICHLORIDES AND CORRELATION OF THEIR P-31 CHEMICAL SHIFTS

Various mono-substituted diethyl arylphosphonates were prepared in good yield by treatment of aryl bromides or iodides with triethyl phosphite in the presence of NiCl2 or alternatively, addition of the aryl grignard reagent to diethyl phosphorochloridate.

Process for the preparation of phosphonic acid dihalides

A process for the preparation of phosphonic acid dihalides of the formula EQU1 IN WHICH R is α, β-unsaturated alkyl, α, β-unsaturated alkyl, phenyl or benzyl and may be further substituted, which comprises reacting corresponding phosphonic or pyrophosphonic acids or their functional derivatives with acid halides of the formula (CO)n Hal2 where n is 1 or 2.