78-50-2 Usage
Chemical Properties
white crystalline powder
Uses
Different sources of media describe the Uses of 78-50-2 differently. You can refer to the following data:
1. Trioctylphosphine oxide (TOPO) is most commonly used as the solvent due to its high boiling point and chemical stability, and its ability to prevent particle aggregation via coordination to the NP surface. trioctylphosphine oxide is a frequently used surfactant, starts to decompose at around 425°C.
The industrial applications of trioctylphosphine oxide, make use of its complexing powers with metals and with hydrogen donor organic compounds. Commercial uses as a solvent extraction reagent are in the recovery of uranium from wet process phosphoric acid and in the recovery of byproduct acetic acid and furfural generated during sulphite wood pulping.
TOPO is a widely used chemical compound in nanocrystal synthesis, for the removal of heavy metals, and the removal of toxins in waste water. TOPO is often used as a ligand stabilizer for colloids in traditional thermal decomposition synthetic techniques.
trioctylphosphine oxide became a nearly irreplaceable solvent (mp 51-52°C) for high-temperature preparation of various type of nanocomposites. TOPO has a very high boiling point (411°C) which is an important prerequisite for the homogeneous nucleation and good crystallinity of the nanoparticles.
2. Tri-n-octylphosphine oxide is a solvent used in the extraction of metals, especially uranium, zirconium and hafnium. It is also used as an auxiliary reagent in the solvent extraction of metals. It is also used to extract hydrogen bonding organic compounds. Further, it is useful as a capping ligand for the production of quantum dots, such as those consisting of cadmium selenide.
3. Catalyst in:Preparation of tetradentate planar-chiral hydroxy-substituted ferrocenecarboxaldimine Schiff base ligandsReactions of allyl esters with hydrosilanesAsymmetric cyanosilylation of aldehydesPreparation of chlorothiol formates from thiols and phosgene
General Description
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Flammability and Explosibility
Nonflammable
Purification Methods
Mason, McCarty and Peppard [J Inorg Nuclear Chem 24 967 1962] stirred a 0.1M solution in *benzene with an equal volume of 6M HCl at 40o in a sealed flask for 48hours, then washed the *benzene solution successively with water (twice), 5% aqueous Na2CO3 (three times) and water (six times). The *benzene and water were then evaporated under reduced pressure at room temperature. Zingaro and White [J Inorg Nucl Chem 12 315 1960] treated a pet ether solution with aqueous KMnO4 (to oxidise any phosphinous acids to phosphinic acids), then with sodium oxalate, H2SO4 and HCl (to remove any manganese compounds). The pet ether solution was slurried with activated alumina (to remove phosphinic acids), filtered, evaporated and the residue was recrystallised from pet ether or cyclohexane at -20o. It can also be recrystallised from EtOH. [Beilstein 4 IV 3466.]
Check Digit Verification of cas no
The CAS Registry Mumber 78-50-2 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 78-50:
(4*7)+(3*8)+(2*5)+(1*0)=62
62 % 10 = 2
So 78-50-2 is a valid CAS Registry Number.
InChI:InChI=1/C24H51OP/c1-4-7-10-13-16-19-22-26(25,23-20-17-14-11-8-5-2)24-21-18-15-12-9-6-3/h4-24H2,1-3H3
78-50-2Relevant articles and documents
Martin et al.
, p. 96,97 (1961)
Photolytic C-O Bond Cleavage with Quantum Dots
Enright, Michael J.,Gilbert-Bass, Kito,Sarsito, Harrison,Cossairt, Brandi M.
, p. 2677 - 2682 (2019/04/25)
Quantum dots are used as photoredox catalysts to drive bond cleavage in lignin model substrates. Cadmium selenide quantum dots selectively cleave C-O bonds with yields comparable to the best transition-metal-based molecular photocatalysts, thereby emulating depolymerization of the β-O-4 linkages that account for 45-60% of all linkers in native lignin. Compared to their molecular catalyst counterparts, the quantum dots demonstrate higher turnover frequencies, higher surface tunability for solvent versatility, and lower catalyst loading under mild, ambient temperature reaction conditions. The robust nature and solvent versatility of these quantum dot photoredox catalysts enable a direct, single-vessel route to convert benzylic alcohols (a majority of species in native and processed lignin) into high-value guaiacols and acetophenones without any prerequisite filtration, purification, or solvent change.
Function of substituents in coordination behaviour, thermolysis and ligand crossover reactions of phosphine oxides
Pavankumar,Goud, E. Veerashekhar,Selvakumar,Kumar, S. K. Ashok,Sivaramakrishna, Akella,Vijayakrishna, Kari,Rao, C. V. S. Brahmananda,Sabharwal,Jha, Prakash C.
, p. 4727 - 4736 (2015/03/03)
Some selected aminophosphine oxides (AmPOs) of the type OP(NMe2)3, OPPh(NMe2)2, OP(NC2H4O)3, OPPh(NC2H4O)2 and their corresponding La(III) and Th(IV) complexes are synthesized and analyzed by FT-IR, 1H-NMR, 31P{1H}-NMR, elemental analysis and TGA data. The coordination behavior of AmPOs was compared with some of the known ligands that include trioctylphosphine oxide (TOPO), tributylphosphate (TBP) and diethylphosphite (DEP). Thermogravimetric analysis of these complexes showed a distinct decomposition trend either by a single step or multi-step elimination of ligand species, which are strongly dependent on the electronic and steric behaviour of substituents on the P=O group and the nature of the metal. Phosphine oxide based La(III) and Th(IV) complexes undergo three unique intermolecular ligand exchange reactions at room temperature: relative competition among phosphine oxides to form a strong complex by exchanging the weaker ligand and complete ligand transfer from La(III) to Th(IV) metal centers. Ligand crossover is well controlled by priority rules and the trend is TOPO > TBP > DEP > AmPO > Ph3PO. This tendency closely agrees with the stability constants of metal complexes. On comparison, Th(IV) complexes showed slightly higher stability than La(III) analogues.
