22874-40-4Relevant articles and documents
One-pot Synthesis of Substituted Quinazolin-4(3H)-ones under Microwave Irradiation
Rad-Moghadam, Kurosh,Khajavi, Mohammad S.
, p. 702 - 703 (1998)
Synthesis of the title compounds by cyclocondensation of anthranilic acid, formic acid (or orthoesters) and an amine in one pot under microwave irradiation takes place in a few minutes.
Transition metal-free synthesis of quinazolinones using dimethyl sulfoxide as a synthon
Lee, Seohoo,Sim, Jaeuk,Jo, Hyeju,Viji, Mayavan,Srinu, Lanka,Lee, Kiho,Lee, Heesoon,Manjunatha, Vishwanath,Jung, Jae-Kyung
supporting information, p. 8067 - 8070 (2019/09/19)
Biologically important quinazolinones have been synthesized from 2-aminobenzamides and DMSO. The key feature of the reaction is the utilization of DMSO as a methine source for intramolecular oxidative annulation. The CNS depressant drug methaqualone has also been synthesized by our methodology. The present method involves the synthesis of quinazolinones with a broad substrate scope and a good yield.
Zirconyl(IV) chloride catalyzed three component one-pot synthesis of quinazolin-4(3H)-ones
Sangshetti, Jaiprakash N.,Kokare, Nagnnath D.,Shinde, Devanand B.
, p. 1289 - 1291 (2008/03/28)
An efficient one-pot method for synthesis of an array of quinazolin-4(3H)-ones from anthranilic acid, triethyl orthoformate, and amines using ZrOCl2 is described. This method offers improvements for the synthesis of quinazolin-4(3H)-ones with r
