22884-83-9

Upstream product

• 67-56-1 methanol 
• 412282-64-5 3-bromo-4-oxo-2,4-diphenyl-butyric acid 
• 124-41-4 sodium methylate 
• 857791-78-7 3-hydroxy-4-oxo-2,4-diphenyl-butyric acid 
• 859932-22-2 3-hydroxy-4-oxo-2,4-diphenyl-butyrohydroxamic acid 
• 2901-29-3 ethyl 2,4-diphenyl-3-oxobutanoate 
• 412282-58-7 4-benzoyl-3-phenyl-oxetan-2-one 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 4370-96-1 4-oxo-2,4-diphenylbutanoic acid 
• 101-97-3 Ethyl 2-phenylethanoate 

Downstream Products

• 7596-43-2 4-methoxy-3,5-diphenyl-5H-furan-2-one 
• 611-73-4 Benzoylformic acid 

Relevant academic research and scientific papers

Methods of inhibiting the advanced glycosylation of proteins using tetramic and tetronic acids and compositions therefor

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises substituted or unsubstituted tetramic and tetronic acids capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with a carbonyl moiety of an early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.