22898-01-7

Basic information

• Product Name: Sodium 2,2,3,3-tetrafluoropropionate
• Synonyms: Tetrapion;Sodium 2,2,3,3-tetrafluoropropionate;flupropanate sodium;2,2,3,3-Tetrafluoropropionic acid sodium;Flupropion;Orga-3045;Tetrapion sodium;2,2,3,3-Tetrafluoropropionic acid, Sodium salt
• CAS NO: 22898-01-7
• Molecular Formula: C₃HF₄O₂*Na
• Molecular Weight: 168.02
• EINECS: 245-311-4
• Mol File: 22898-01-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 140.7 °C at 760 mmHg
• Flash Point: 38.9 °C
• Appearance: /
• Vapor Pressure: 3.47mmHg at 25°C
• CAS DataBase Reference: Sodium 2,2,3,3-tetrafluoropropionate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium 2,2,3,3-tetrafluoropropionate(22898-01-7)
• EPA Substance Registry System: Sodium 2,2,3,3-tetrafluoropropionate(22898-01-7)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 22898-01-7(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to pale yellow transparent liquid

Uses

Different sources of media describe the Uses of 22898-01-7 differently. You can refer to the following data:
1. Agricultural chemical.
2. Sodium 2,2,3,3-Tetrafluoropropionate is used in methods and formulations for preventing downward migration of agricultural materials. It is a salt form of 2,2,3,3-Tetrafluoropropanoic Acid(T292900) is used as a herbicide.

Hazard

Moderately toxic by skin contact. Low tox- icity by ingestion.

InChI:InChI=1/C3H2F4O2.Na/c4-1(5)3(6,7)2(8)9;/h1H,(H,8,9);/q;+1/p-1

Synthetic route

5-amino-1,1,2,2-tetrafluoro-4-hexen-3-one (72721-34-7) → Na-2,2,3,3-Tetrafluoropropionate (22898-01-7)

Conditions	Yield
With potassium hydroxide In ethanol for 8h; Heating;

1,1,2,2-tetrafluoro-5-(N-methylamino)-hex-4-en-3-one (72721-37-0) → Na-2,2,3,3-Tetrafluoropropionate (22898-01-7) + acetone (67-64-1) + methylamine (74-89-5)

Conditions	Yield
With sodium hydroxide In ethanol at 20℃; Rate constant; Mechanism;

5-amino-1,1,2,2-tetrafluoro-4-hexen-3-one (72721-34-7) → Na-2,2,3,3-Tetrafluoropropionate (22898-01-7) + acetone (67-64-1) + NH3

Conditions	Yield
With sodium hydroxide In ethanol at 20℃; Rate constant; Mechanism;

1,1,2,2-tetrafluoro-5-phenyl-5-amino-4-penten-3-one (123824-65-7) → Na-2,2,3,3-Tetrafluoropropionate (22898-01-7) + acetophenone (98-86-2) + NH3

Conditions	Yield
With sodium hydroxide In ethanol at 20℃; Rate constant; Mechanism;

3,3-dimethylbutan-2-one O-(3-phenylpropyl) oxime + Na-2,2,3,3-Tetrafluoropropionate (22898-01-7) + acetic acid (64-19-7) → C18H23F4NO3 + C21H23F8NO5 + C20H25F4NO5

Conditions	Yield
With sodium nitrate; oxygen; palladium diacetate at 100℃; for 0.666667h; Schlenk technique;	A 30% B 15% C 19%

Upstream product

• 72721-34-7 5-amino-1,1,2,2-tetrafluoro-4-hexen-3-one 
• 72721-37-0 1,1,2,2-tetrafluoro-5-(N-methylamino)-hex-4-en-3-one 
• 123824-65-7 1,1,2,2-tetrafluoro-5-phenyl-5-amino-4-penten-3-one 

Relevant articles and documents

HYDROLYSIS OF FLUOROALKYL-CONTAINING β-AMINOVINYL KETONES

The kinetics of hydrolysis of fluoroalkyl-containing β-aminovinyl ketones R1C(O)CHC(NHR3)R2, in which the substituents CF3 and HCF2CF2 are in the ketone (R1) or enamine parts of the molecule (R2), was studied.In acid (pH 10) media, they hydrolyze with the formation of the corresponding amines and β-diketones.In an alkaline medium, the β-diketones undergo cleavage to fluorinated acids and methyl ketones.The rate constants of hydrolysis in an acid medium change within a range of four orders, depensdng on the nature of the substituents.The presence of a fluoroalkyl group at the enamine reaction center increases the hydrolysis rate.In an alkaline medium, the rate constants vary within one order.