22945-63-7

Usage

General Description

2-(2-METHOXYBENZOYL)PYRIDINE is a chemical compound with the molecular formula C15H13NO3. It is a pyridine derivative with a benzoyl group and a methoxy group attached to the pyridine ring. 2-(2-METHOXYBENZOYL)PYRIDINE is used in organic synthesis and pharmaceutical research as a building block for the preparation of various bioactive molecules. Its unique structure and properties make it a valuable intermediate in the production of pharmaceuticals and agrochemicals. The compound may also have potential therapeutic applications due to its ability to interact with biological targets. Overall, 2-(2-METHOXYBENZOYL)PYRIDINE is a versatile chemical that is utilized in various scientific and industrial applications.

InChI:InChI=1/C13H11NO2/c1-16-12-8-3-2-6-10(12)13(15)11-7-4-5-9-14-11/h2-9H,1H3

Upstream product

• 100-70-9 2-Cyanopyridine 
• 578-57-4 2-bromoanisole 
• 109-06-8 α-picoline 
• 941279-81-8 2,4-dimethyl-3-(pyridin-2-ylmethyl)pentan-3-ol 
• 35854-43-4 2-[(2-methoxyphenyl)methyl]pyridine 
• 109-04-6 2-bromo-pyridine 
• 606-45-1 2-methoxybenzoic acid methyl ester 
• 67-56-1 methanol 
• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 27652-91-1 α-(2-methoxyphenyl)-2-pyridinemethanol 

Downstream Products

• 1350476-52-6 (R)-(2-methoxyphenyl)(pyridin-2-yl)methanol 
• 52009-05-9 2-hydroxyphenyl radical 

Relevant academic research and scientific papers

Compounds for and methods of treating diseases

The present invention provides heterocyclic compounds of formula (I) that modulate biological metals and to pharmaceutical compositions containing such compounds. The invention particularly relates to compounds that modulate iron and to compounds for the treatment of diseases, particularly neurological diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), Alzheimer-type dementia, Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and multiple system atrophy (MSA).

COMPOUNDS FOR AND METHODS OF TREATING DISEASES

The present invention provides compounds that modulate biological metals and to pharmaceutical compositions containing such compounds. The invention particularly relates to imidazo[1,5-a]pyridine compounds that modulate iron and are useful for the treatment of diseases, particularly neurological diseases such as Parkinson's disease (PD), Alzheimer's 5 disease (AD), Alzheimer-type dementia, Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and multiple system atrophy (MSA).

Pd(OAc)2-catalysed regioselective alkoxylation of aryl (β-carbolin-1-yl)methanones via β-carboline directed ortho-C(sp2)-H activation of an aryl ring

Synthesis of (2-alkoxyphenyl)(9H-pyrido[3,4-b]indol-1-yl)methanone via Pd(OAc)2-catalyzed regioselective alkoxylation of aryl (β-carbolin-1-yl) methanones employing β-carboline directed ortho-C(sp2)-H activation of an aryl ring under

Isolation and characterization of a trinuclear cobalt complex containing trigonal-prismatic cobalt in secondary alcohol aerobic oxidation

An unusual trinuclear cobalt complex was successfully isolated and characterized in the Co(OAc)2·4H2O-catalyzed aerobic oxidation of pyridine-based secondary alcohols. In this complex, a cobalt ion (the one in the middle, labeled Co2) has a novel trigonal-prismatic structure coordinated with six oxygen atoms from the substrate. The molecular oxygen present in air plays a major role in enabling this transformation to be catalytic. This aerobic catalytic reaction is very selective to pyridine-based secondary alcohols over primary alcohols.

Generation and reactions of heteroaromatic lithium compounds by using in-line mixer in a continuous flow microreactor system at mild conditions

A lithium-halogen exchange reaction procedure was applied to introduce electrophilic substituents to the heteroaromatics, which exhibited potential in the syntheses of pharmaceutical intermediates. In this contribution, generation and reactions of heteroa

Synthesis of aryl(di)azinyl ketones through copper- and iron-catalyzed oxidation of the methylene group of aryl(di)azinylmethanes

Sustainable Oxidations: An oxidation method to transform aryl(di)azinylmethanes into aryl(di)azinyl ketones is described. Base metals (copper and iron) as catalysts in combination with O2 as the oxidant are used, which makes this method sustainable. The utility of this method is illustrated by the synthesis of 6-(4-methylbenzoyl)pyridine-2-carbaldehyde, which is an intermediate in the preparation of the drug Acrivastine. Copyright

Ruthenium-catalyzed enantioselective hydrogenation of aryl-pyridyl ketones

Various substituted aryl-pyridyl ketones were hydrogenated in the presence of Ru-XylSunPhos-Daipen bifunctional catalytic system with enantiomeric excesses up to 99.5%. Upon introduction of a readily removable ortho-bromo atom to the phenyl ring, enantiomerically enriched 4-chlorophenylpyridylmethanol was obtained by hydrogenation method with 97.3% ee, which provided an important chiral intermediate for some histamine H1 antagonists.