22952-14-3

Basic information

• Product Name: Benzene, 1,1'-[1,2-ethanediylbis(sulfonyl)]bis[4-methyl-
• Synonyms: 1,2-ditosylate-ethane;1.2-Di-p-tolylsulfon-aethan;1.2-Bis-p-tolylsulfon-aethan
• CAS NO: 22952-14-3
• Molecular Formula: C16H18O4S2
• Molecular Weight: 338.449
• Mol File: 22952-14-3.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-[1,2-ethanediylbis(sulfonyl)]bis[4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-[1,2-ethanediylbis(sulfonyl)]bis[4-methyl-(22952-14-3)
• EPA Substance Registry System: Benzene, 1,1'-[1,2-ethanediylbis(sulfonyl)]bis[4-methyl-(22952-14-3)

Safety Data

• Hazardous Substances Data: 22952-14-3(Hazardous Substances Data)

Upstream product

• 5535-52-4 tolyl vinyl sulfone 
• 38674-90-7 4-Acetamido-N-phenylaniline 
• 39837-39-3 1,1,2-tris-(toluene-4-sulfonyl)-ethane 
• 32018-25-0 1-(toluene-4-sulfonyl)-2-p-tolylsulfanyl-ethane 
• 64-17-5 ethanol 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 106-93-4 ethylene dibromide 
• 15717-50-7 E-ditosylethene 
• 80-41-1 2-chloroethyl tosylate 
• 16336-54-2 p-tolyl vinyl sulfide 
• 34726-90-4 trans-1-(toluene-4-sulfonyl)-2-p-tolylsulfanyl-ethene 
• 98-59-9 p-toluenesulfonyl chloride 
• 15310-28-8 bis(4-methylphenylsulfonyl)methane 
• 144488-85-7 1-(toluene-4-sulfinyl)-2-(toluene-4-sulfonyl)-ethene 

Downstream Products

• 22381-54-0 2-(p-tolylsulfonyl)ethanol 
• 3405-96-7 diethyl-[2-(toluene-4-sulfonyl)-ethyl]-amine 
• 32018-25-0 1-(toluene-4-sulfonyl)-2-p-tolylsulfanyl-ethane 
• 65972-15-8 2-ethoxyethyl p-tolyl sulphone 
• 28611-88-3 PhOCH₂CH₂Ts 
• 536-57-2 p-toluene sulfinic acid 
• 64-17-5 ethanol 
• 106-45-6 para-thiocresol 
• 35777-35-6 bis-[2-(toluene-4-sulfonyl)-ethyl]-amine 
• 22381-53-9 2-chloroethyl-p-toluenesulfonate 
• 57023-02-6 (2-iodo-ethyl)-p-tolyl sulfone 
• 408339-55-9 benzoic acid 2-(toluene-4-sulfonyl)ethyl ester 
• 109184-88-5 diethyl-[2-(4-methyl-3-nitro-benzenesulfonyl)-ethyl]-amine 
• 1593215-45-2 C₂₂H₁₈N₄O₂ 

Relevant articles and documents

Efficient synthesis of aliphatic sulfones by Mg mediated coupling reactions of sulfonyl chlorides and aliphatic halides

Sulfonyl chlorides were reduced to anhydrous sulfinate salts with magnesium under sonication. These sulfinates were alkylated to sulfones with alkyl chlorides in the presence of catalytic sodium iodide under sonication. A variety of aliphatic sulfones was efficiently prepared by this one-pot two-step procedure.

INNOVATIVE APPROACH TO THE SYNTHESIS OF SULPHIDES AND THEIR CORRESPONDING SULPHONES

A general and efficient synthetic approach to aryl-aryl bis-sulphides with aliphatic or aromatic bridges via the nucleophilic aromatic substitution (SNAr) of cyclopentadienyliron arene complexes with a number of dithiols followed by photolytic demetallation is presented in this work.The oxidation of the bis(cyclopentadienyliron) arene complexes containing bis-sulphide linkages with 3-chlorobenzoic acid gave their corresponding sulphones in very good yield (70-95percent).Mixed ether/sulphide and ether/sulphone complexes were also prepared following the same synthetic strategy.Reactions of sulphide and sulphone diiron complexes with terminal chloro groups with a number of oxygen, sulphur and carbon nucleophiles allowed for the functionalization of these complexes.The use of photolytic demetallation as a means of liberating the modified arene ligands proved to be very successful.The mild conditions, high yields and low cost of the starting iron complexes make this method one of the most general and practical routes to sulphide and sulphone compounds.