23056-35-1Relevant academic research and scientific papers
Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
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, (2008/06/13)
Carbapenems of the formula: STR1 are disclosed as useful antibacterial agents. Pharmaceutical compositions and methods of use are also disclosed.
Pyrido[3,4-e]-1,2,4-triazines and related heterocycles as potential antifungal agents
Reich,Fabio,Lee,Kuck,Testa
, p. 2474 - 2485 (2007/10/02)
The preparation and biological activities of a series of pyrido[3,4-e]-1,2,4-triazines, 1,2,4-triazino[5,6-c]quinolines, and related fused triazines are described. Methyl, amino, and acylamino substituents were placed in the pyridyl ring of the former system. Other structural modifications included various alkyl, cycloalkyl, substituted phenyl, and heterocyclic groups in the 3-position of these ring systems. In agar dilution assays, actives in this series inhibited strains of Candida, Aspergillus, Mucor, and Trychophyton species at MIC's of ≤ 16 μg/mL.
Nitro, amino and aroylamino-N-phenylpyridinamines in a process for preparing pyrido[1,4]benzodiazepines
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, (2008/06/13)
Nitro, amino and aroylamino-N-phenylpyridinamines as chemical intermediates and/or having antidepressant activity having the formula STR1 wherein R3 is nitro, amino or aroylamino, and Q is hydrogen, --NR1 R2 or halogen are disclosed in a process for preparing pyrido[1,4]benzodiazepines.
