18614-66-9

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Hydroxy-2-methyl-3-nitropyridine is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex organic molecules, contributing to the development of new drugs.
Used in Agrochemical Production:
In the agrochemical industry, 4-Hydroxy-2-methyl-3-nitropyridine is used as a building block in the creation of various agrochemicals, aiding in the development of pesticides and other agricultural products.
Used in Dye and Pigment Manufacturing:
4-Hydroxy-2-methyl-3-nitropyridine is utilized in the production of dyes and pigments due to its chemical structure that can impart color and stability to these products, making it suitable for a range of applications in the dye and pigment industry.

Upstream product

• 18614-65-8 2-methyl-4-pyridinol nitrate 
• 18437-58-6 3-methyl-4-pyridinamine 
• 5470-66-6 2-methyl-4-nitropyridine N-oxide 
• 931-19-1 2-methylpyridine N-oxide 
• 24103-75-1 4-methoxy-2-methylpyridine 
• 6890-60-4 4-methoxy-2-methylpyridine 1-oxide 
• 18615-86-6 2-Methyl-4-hydroxypyridine 

Downstream Products

• 121845-73-6 5-methylpyrido[3,4-e]-1,2,4-triazine 
• 121845-74-7 3,5-dimethylpyrido[3,4-e]-1,2,4-triazine 
• 121845-75-8 5-methyl-3-(4-pyridinyl)pyrido[3,4-e]-1,2,4-triazine 
• 23056-35-1 4-chloro-2-methyl-3-nitropyridine 
• 1256806-33-3 7-bromo-1H-pyrazolo[4,3-b]pyridine 
• 23056-49-7 4-bromo-2-methyl-3-nitropyridine 

Relevant academic research and scientific papers

ANTIBIOTIC COMPOUNDS

The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.

A Unified Approach to the Isomeric α-, β-, γ-, and δ-Carbolines via their 6,7,8,9-Tetrahydro Counterparts

A cross-coupling/reductive cyclization protocol has been employed in a unified approach to all four carbolines. So, for example, the 2-nitropyridine 8, which is readily prepared through an efficient palladium-catalyzed Ullmann cross-coupling reaction, is reductively cyclized under conventional conditions to give 6,7,8,9-tetrahydro-α-carboline that is itself readily aromatized to give α-carboline (1).

PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5

The present invention provides ALK5 inhibitors of the formula (I) wherein the variables are as defined herein. Also provided are pharmaceutical compositions, methods of making the compounds and intermediates thereof; and methods of using the compounds.

Pyrido[3,4-e]-1,2,4-triazines and related heterocycles as potential antifungal agents

The preparation and biological activities of a series of pyrido[3,4-e]-1,2,4-triazines, 1,2,4-triazino[5,6-c]quinolines, and related fused triazines are described. Methyl, amino, and acylamino substituents were placed in the pyridyl ring of the former system. Other structural modifications included various alkyl, cycloalkyl, substituted phenyl, and heterocyclic groups in the 3-position of these ring systems. In agar dilution assays, actives in this series inhibited strains of Candida, Aspergillus, Mucor, and Trychophyton species at MIC's of ≤ 16 μg/mL.