23339-16-4

Usage

Uses

Used in Biochemical Research:
Ethyl 2,3-dideoxyhexopyranoside is utilized as a research compound for studying the interactions between sugars and other biomolecules. Its unique structure allows for the investigation of carbohydrate recognition and binding processes, which are crucial for understanding various biological functions and mechanisms.
Used in Pharmaceutical Development:
In the pharmaceutical industry, ethyl 2,3-dideoxyhexopyranoside serves as a key intermediate in the synthesis of various drug candidates. Its hydrophobic nature and structural features make it a valuable component in the development of novel therapeutic agents targeting specific biological pathways or receptors.
Used in Drug Delivery Systems:
Ethyl 2,3-dideoxyhexopyranoside is employed as a component in drug delivery systems to enhance the solubility, stability, and bioavailability of pharmaceutical compounds. Its hydrophobic property can improve the encapsulation of drugs in carriers, facilitating targeted and controlled release of therapeutic agents.
Used in Chemical Synthesis:
As a versatile building block, ethyl 2,3-dideoxyhexopyranoside is used in the synthesis of a range of organic compounds, including complex carbohydrates, natural products, and other bioactive molecules. Its unique structure provides opportunities for the development of new synthetic routes and methodologies in organic chemistry.

Upstream product

• 596815-90-6 O⁴,O⁶-diacetyl-D-erythro-2,3-dideoxy-hexose 
• 122-51-0 orthoformic acid triethyl ester 
• 1592771-19-1 C₁₈H₃₄O₆Si 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 2873-29-2 D-glucal triacetate 
• 3323-72-6 ethyl 4,6-di-O-acetyl-2,3-dideoxy-α-D-erythrohex-2-enopyranoside 
• 55735-69-8 ethyl 4,6-di-O-acetyl-2,3-dideoxy-α-D-erythrohexopyranoside 
• 23339-15-3 ethyl 2,3-dideoxy-α-D-erythro-hex-2-enopyranoside 

Downstream Products

• 104784-32-9 (2R,3S,6S)-6-ethoxy-3-phenylmethoxy-2-phenylmethoxymethyltetrahydropyran 
• 495378-93-3 ethyl 2,3-dideoxy-6-O-trityl-α-D-erythro-hexopyranoside 
• 177723-39-6 ethyl 6-O-tosyl-2,3-dideoxy-α-D-erythro-pyranoside 
• 452084-61-6 tert-butyl (3R,4R)-3-azido-4-(benzyloxy)azepane-1-carboxylate 
• 1054623-84-5 (3R,4R)-4-[4-(2-Benzyloxy-6-benzyloxycarbonyl-benzoyl)-3,5-bis-methoxymethoxy-benzoyloxy]-3-[4-(tert-butyl-dimethyl-silanyloxy)-benzoylamino]-azepane-1-carboxylic acid tert-butyl ester 
• 452084-66-1 tert-butyl (3S,4R)-4-(benzyloxy)-3-hydroxyazepane-1-carboxylate 
• 1053650-96-6 Acetic acid (2R,3S,6S)-6-ethoxy-2-trityloxymethyl-tetrahydro-pyran-3-yl ester 
• 141458-83-5 4,6-di-O-benzyl-2,3-dideoxy-D-erythro-hexopyranose 
• 141458-86-8 (S)-2,2-difluoro-1,3-(dibenzyloxy)tetradec-6-ene 
• 141458-84-6 (2R,3S)-1,3-dibenzyloxy-2-hydroxytetradec-6-ene 

Relevant academic research and scientific papers

Synthesis of the GHIJKL Fragment of Gymnocin-B

The GHIJKL fragment of gymnocin-B was synthesized using the oxiranyl anion strategy. The first highlight of the synthesis is the bromoketone cyclization reaction on the oxepane ring to construct the fused bisoxepane GH ring. The second key step is the int

Novel optically active 1,3-aminoalcohols derived from D-glucal

A series of ethyl(phenyl) 6-amino-2,3,6-trideoxy-α-D-glucopyranosides (amino = piperidino (Pip), pyrrolidino (Pyr), azetidino (Az), Bu2N) have been prepared from tri-O-acetyl-D-glucal to obtain catalysts for asymmetric synthesis and the starting compounds for the syntheses of other bidentate ligands.

Total synthesis of enantiomerically pure (-)-Balanol

The total synthesis of enantiomerically pure (-)-Balanol (1), using tri-O-acetyl-D-glucal as a chiral template for the central azepane fragment is described.

Stereospecific synthesis of ethyl 4, 6-diamino-α-D-threo-hexopyranoside

A stereospecific synthesis of the title compound from D-glucose is reported.

Synthesis of (2R,3S)-3-[(benzyloxycarbonyl)oxy]-2-fluorotetradecanoic acid

Optically active threo-3-[(benzyloxycarbonyl)oxy]-2-fluorotetradecanoic acid, (2R,3S)-11, was synthesized from 3,4,6-tri-O-acetyl-D-glucal via methyl uronate derivative (5). Reaction of 5 with octylidene triphenylphosphorane followed by treatment with DAS

ENANTIOSPECIFIC SYNTHESIS OF (R)-(+)-α-LIPOIC ACID FROM D-GLUCOSE

The first enantiospecific synthesis of natural (R)-(+)-α-lipoic acid in 13 steps starting from D-glucose is described.