66166-17-4

Basic information

• Product Name: Benzamide, N-(2-hydroxy-1,2-diphenylethyl)-
• CAS NO: 66166-17-4
• Molecular Formula: C21H19NO2
• Molecular Weight: 317.387
• Mol File: 66166-17-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(2-hydroxy-1,2-diphenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(2-hydroxy-1,2-diphenylethyl)-(66166-17-4)
• EPA Substance Registry System: Benzamide, N-(2-hydroxy-1,2-diphenylethyl)-(66166-17-4)

Safety Data

• Hazardous Substances Data: 66166-17-4(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 23364-43-4 N-benzylidene-dl-diphenylhydroxyethylamine 
• 98-88-4 benzoyl chloride 
• 77444-20-3 N-(2-Chloro-1,2-diphenylethyl)benzamide 
• 102478-96-6 1,2-Diphenyl-2-benzoyloxyethylamine hydrochloride 
• 530-36-9 erythro-2-amino-1,2-diphenylethanol 
• 1689-71-0 2,3-diphenyloxirane 
• 5959-42-2 (+/-)-erythro-α'-amino-bibenzyl-α-ol; hydrochloride 
• 451-40-1 phenyl benzyl ketone 
• 1484-50-0 desyl bromide 
• 32493-66-6 2-(2-oxo-1,2-diphenylethyl)isoindoline-1,3-dione 
• 885-75-6 2-amino-1,2-diphenyl-ethanone; hydrochloride 
• 6942-03-6 α-benzamidylbenzyl phenyl ketone 
• 71028-20-1 (+/-)-benzoic acid-(threo-α'-amino-bibenzyl-α-yl ester); hydrochloride 

Downstream Products

• 71028-20-1 (+/-)-benzoic acid-(threo-α'-amino-bibenzyl-α-yl ester); hydrochloride 
• 66166-25-4 1,4-diphenylisoquinoline 
• 34987-64-9 1,3-diphenylisoquinoline 
• 71027-98-0 trans-2,4,5-triphenyl-Δ²-oxazoline 
• 66730-28-7 N-(1,2-diphenylethyl)benzamide 

Relevant articles and documents

Asymmetric Transfer Hydrogenation: Dynamic Kinetic Resolution of α-Amino Ketones

A series of α-amino ketones were reduced using asymmetric transfer hydrogenation (ATH) through a dynamic kinetic resolution (DKR). The protecting group was matched to the reducing agent, and following optimization, a series of substrates were investigated, giving products in high diastereoselectivity, over 99% ee in several cases and full conversion. The methodology was applied to the enantioselective synthesis of an MDM2-p53 inhibitor precursor.

REACTIVITY OF N,N-DICHLOROURETHANES. XI. ADDITION OF N,N-DICHLOROURETHANES TO trans-STILBENE

N,N-Dichlorourethanes add readily to trans-stilbene with the formation of alkyl N-chloro-N-(2-chloro-1,2-diphenylethyl)carbamates, which give alkyl N-(2-chloro-1,2-diphenylethyl)carbamates when treated with an aqueous solution of sodium sulfite or thiosul