2348-89-2

Usage

Synthesis Reference(s)

Synthetic Communications, 22, p. 3089, 1992 DOI: 10.1080/00397919209409258Synthesis, p. 395, 1991

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 
• 185-94-4 bicyclo[2.1.0]pentane 

Downstream Products

• 876-05-1 cis-1,3-cyclopentanedicarboxylic acid 
• 3400-45-1 cyclopentanecarboxylic acid 
• 13668-59-2 3-hydroxymethyl-cyclopentene 
• 7686-77-3 3-cyclopentene-1-carboxylic acid 
• 6240-43-3 cis-3-methylcyclopentanecarboxylic acid 
• 4541-43-9 acide methyl-2 cyclopentanecarboxylique-1 cis 
• 108384-35-6 methyl 3-oxocyclopent-1-enecarboxylate 
• 13668-61-6 (cyclopent-2-eneyl)acetic acid 
• 137709-64-9 N-<(1'β,4'β,6'α)-6'-fluoro-4'-triphenylmethoxymethylcyclopentylaminocarbonyl>-3-methoxy-2-methylprop-2-enamide 
• 129746-07-2 (1β,2α,3β)-2-fluoro-3-triphenylmethoxymethylcyclopentylamine 
• 127530-14-7 (1'β,4'β,6'α)-1-<6'-fluoro-4'-(hydroxymethyl)cyclopentyl>-5-methylpyrimidine-2,4(1H,3H)-dione 
• 119895-91-9 2-exo-triphenylmethoxymethyl-6-oxabicyclo<3.1.0>hexane 
• 119895-90-8 triphenylmethoxymethylcyclopent-2-ene 
• 66857-07-6 benzyl 2-(2-cyclopentenecarbonyl)-1-cyclopentenyl carbonate 

Relevant academic research and scientific papers

(Lig)Ni(0) induced preparation of mono- and dicarboxylic acids from cyclopentene and carbon dioxide

Cyclopentene is shown to be an ideal substrate for coupling reactions with (Lig)nickel(0) systems. By variation of the ligands and addition of promoters, it is possible by successive application of carbon dioxide or carbon monoxide to prepare highly selectively series of cyclopentane- and cyclopentenecarboxylic acids (six examples), 4, 5, 6, 11, 14, 15, cyclopentanedicarboxylic acids (three examples), 7, 8, 12, or 2-hydroxycyclopentanecarboxylic acid (9) in good yields. The C5-skeleton is retained in the products.