23612-46-6

Basic information

• Product Name: N-(3-Methyl-2-pyridyl)benzamide
• Synonyms: N-(3-Methyl-2-pyridyl)benzamide;N-(3-methyl-2-pyridinyl)benzamide
• CAS NO: 23612-46-6
• Molecular Formula: C₁₃H₁₂N₂O
• Molecular Weight: 212.25
• Mol File: 23612-46-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 280.7°C at 760 mmHg
• Flash Point: 123.6°C
• Appearance: /
• Density: 1.193g/cm³
• Vapor Pressure: 0.00373mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: N-(3-Methyl-2-pyridyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Methyl-2-pyridyl)benzamide(23612-46-6)
• EPA Substance Registry System: N-(3-Methyl-2-pyridyl)benzamide(23612-46-6)

Safety Data

• Hazardous Substances Data: 23612-46-6(Hazardous Substances Data)

Usage

General Description

N-(3-Methyl-2-pyridyl)benzamide is a chemical compound with the molecular formula C13H12N2O. It is an amide derivative of 3-methyl-2-pyridine and benzoyl chloride. N-(3-Methyl-2-pyridyl)benzamide is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a reagent in the preparation of various organic compounds. N-(3-Methyl-2-pyridyl)benzamide may have potential applications in medicinal chemistry and material science due to its unique chemical structure and properties. However, its toxicological properties and potential hazards have not been widely studied, so precautions should be taken when handling this compound.

InChI:InChI=1/C13H12N2O/c1-10-6-5-9-14-12(10)15-13(16)11-7-3-2-4-8-11/h2-9H,1H3,(H,14,15,16)

Upstream product

• 1603-40-3 3-methylpyridin-2-ylamine 
• 93-97-0 benzoic acid anhydride 
• 100-52-7 benzaldehyde 
• 70-11-1 α-bromoacetophenone 
• 100-41-4 ethylbenzene 
• 98-85-1 1-Phenylethanol 
• 98-86-2 acetophenone 
• 102-96-5 (2-nitroethenyl)benzene 
• 536-74-3 phenylacetylene 
• 98-88-4 benzoyl chloride 

Downstream Products

• 10586-52-4 2-phenyl-1H-pyrrolo[2,3-b]pyridine 
• 4931-20-8 8-methyl-2-phenyl-[1,2,4]triazolo[1,5-a]pyridine 
• 1439397-11-1 1-(4-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)cyclobutanamine 
• 1439397-16-6 tert-butyl 1-(4-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)cyclobutylcarbamate 
• 945608-15-1 3-iodo-1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridine 
• 1427204-31-6 N-(dimethylcarbamoyl)-N-(3-methylpyridin-2-yl)benzamide 

Relevant articles and documents

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Chemodivergent synthesis of: N -(pyridin-2-yl)amides and 3-bromoimidazo[1,2- a] pyridines from α-bromoketones and 2-aminopyridines

N-(Pyridin-2-yl)amides and 3-bromoimidazo[1,2-a]pyridines were synthesized respectively from α-bromoketones and 2-aminopyridine under different reaction conditions. N-(Pyridin-2-yl)amides were formed in toluene via C-C bond cleavage promoted by I2/s

Ce(III)-catalyzed highly efficient synthesis of pyridyl benzamides from aminopyridines and nitroolefins without external oxidants

An efficient synthesis of a variety of pyridyl benzamides from 2-aminopyridines and nitroolefins is described. This rare-earth-metal-catalyzed reaction provides the corresponding products with broad substrate scope in moderate to excellent yields, in the absence of additives and external oxidants. Water is used as the source of the carbonyl oxygen atom in pyridyl benzamides. Furthermore, 2-substituted oxazolo[4,5-b]pyridines are formed in good yields under the standard conditions when 2-aminopyridin-3-ols are used as the substrates.