236406-15-8

Basic information

• Product Name: 4-BENZYLOXYCARBONYLAMINO-4-METHYL-PIPERIDINE
• Synonyms: 4-BENZYLOXYCARBONYLAMINO-4-METHYL-PIPERIDINE;4-BENZYLOXYCARBONYLAMINO-4-METHYL-PIPERIDINE HYDROCHLORIDE;BENZYL 4-METHYLPIPERIDIN-4-YLCARBAMATE;4-BENZYLOXYCARBONYLAMIO-4-METHYL-PIPERIDINE HYDROCHLORIDE;Carbamic acid, (4-methyl-4-piperidinyl)-, phenylmethyl ester (9CI);4-BENZOXYCARBONYLAMINO-4-METHYL-PIPERIDINE;4-BENZYLOXYCARBONYLAMIO-4-METHYL-PIPERIDINE;(4-Methyl-piperidin-4-yl)-carbamic acid benzyl ester
• CAS NO: 236406-15-8
• Molecular Formula: C₁₄H₂₀N₂O₂
• Molecular Weight: 248.32
• Product Categories: N-CBZ
• Mol File: 236406-15-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 394.9 °C at 760 mmHg
• Flash Point: 192.6 °C
• Appearance: /
• Density: 1.11 g/cm³
• Vapor Pressure: 1.91E-06mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: 2-8°C(protect from light)
• PKA: 12.54±0.20(Predicted)
• CAS DataBase Reference: 4-BENZYLOXYCARBONYLAMINO-4-METHYL-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXYCARBONYLAMINO-4-METHYL-PIPERIDINE(236406-15-8)
• EPA Substance Registry System: 4-BENZYLOXYCARBONYLAMINO-4-METHYL-PIPERIDINE(236406-15-8)

Safety Data

• Hazardous Substances Data: 236406-15-8(Hazardous Substances Data)

Usage

General Description

4-Benzyloxycarbonylamino-4-methyl-piperidine is a chemical compound with the molecular formula C17H24N2O2. It is a piperidine derivative with a benzyl and carbonylamino group attached to the nitrogen atom. This chemical is used in organic synthesis as an intermediate or building block in the preparation of pharmaceutical compounds and other organic molecules. It has potential applications in the synthesis of drugs, agrochemicals, and other fine chemicals. The structure and properties of 4-Benzyloxycarbonylamino-4-methyl-piperidine make it suitable for use in various chemical reactions and as a key component in the development of new compounds.

InChI:InChI=1/C14H20N2O2/c1-14(7-9-15-10-8-14)16-13(17)18-11-12-5-3-2-4-6-12/h2-6,15H,7-11H2,1H3,(H,16,17)

Upstream product

• 100-51-6 benzyl alcohol 
• 189442-87-3 ethyl tert-butyl 4-methylpiperidine-1,4-dicarboxylate 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 1126-09-6 4-carbethoxypiperidine 
• 343788-69-2 4-amino-4-methyl-piperidine-1-carboxylic acid tert-butyl ester 
• 501-53-1 benzyl chloroformate 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 189321-63-9 1-(tert-butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid 
• 724790-59-4 4-methyl-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-methyl ester 
• 124443-68-1 1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate 
• 236406-14-7 1,1-dimethylethyl 4-methyl-4-({[(phenylmethyl)oxy]carbonyl}amino)-1-piperidinecarboxylate 

Downstream Products

• 676559-90-3 (5'-chloro-4-methyl-3,4,5,6-tetrahydro-2H-(1,2')bipyridinyl-4-yl)-carbamic acid benzyl ester 
• 1067915-27-8 benzyl 1-(5-fluoro-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinolin-8-yl)-4-methylpiperidin-4-ylcarbamate 
• 1067915-26-7 benzyl 1-(6-fluoro-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinolin-8-yl)-4-methylpiperidin-4-ylcarbamate 
• 1067914-49-1 benzyl 1-(2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinolin-8-yl)-4-methylpiperidin-4-ylcarbamate 
• 1421928-79-1 ethyl 2-(4-(((benzyloxy)carbonyl)amino)-4-methylpiperidin-1-yl)acetate 
• 1187321-76-1 C₂₅H₃₅N₃O₉ 
• 1187321-74-9 C₂₈H₃₉N₃O₉ 
• 1187321-94-3 C₂₅H₃₅N₃O₈ 
• 1187322-20-8 C₂₄H₃₃N₃O₈ 
• 1187321-77-2 2-(4-amino-4-methylpiperidin-1-yl)-N-(6,7-dihydroxy-2,2-dimethyltetrahydro-[1,3]-dioxolo[4,5-b]pyran-3a-ylmethyl)-2-oxo-acetamide 
• 1187321-73-8 (4-benzyloxycarbonylamino-4-methyl piperidin-1-yl)-oxo-acetic acid 
• 1075238-05-9 (1R)-1-[(4-isocyanato-4-methyl-1-piperidinyl)methyl]-1,2,5,6-tetrahydro-4H,9H-imidazo[1,2,3-ij]-1,8-naphthyridine-4,9-dione 
• 1187321-83-0 C₂₆H₃₈N₂O₁₀S 
• 1187321-78-3 C₂₆H₃₈N₂O₇ 

Relevant articles and documents

Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones

The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions.

COMPOUNDS AND METHODS

The present invention relates to novel retinoid-related orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.

IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS

Compounds of Formula (I) in which A, B, R1, R1a, R2, R3, R4, R5, R6, R7 and R8 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. Particular compounds of this invention have also been found to be inhibitors of Pim-1