23813-24-3

Basic information

• Product Name: METHYL6-METHOXY-2-PYRAZINECARBOXYLATE
• Synonyms: METHYL6-METHOXY-2-PYRAZINECARBOXYLATE;2-Methoxy-6-pyrazinecarboxylic acid methyl ester;6-Methoxy-2-pyrazinecarboxylic acid methyl ester;6-Methoxypyrazine-2-carboxylic acid methyl ester;6-Methoxy-2-Methoxycarbonylpyrazine;Methyl 6-Methoxypyrazine-2-carboxylate;ethyl 6-methoxypyrazine-2-carboxylate
• CAS NO: 23813-24-3
• Molecular Formula: C7H8N2O3
• Molecular Weight: 168.15002
• Mol File: 23813-24-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 81.5-82℃
• Boiling Point: 249.9±35.0℃ (760 Torr)
• Flash Point: 105.0±25.9℃
• Appearance: /
• Density: 1.220±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.022mmHg at 25°C
• Refractive Index: 1.505
• Storage Temp.: 2-8°C
• PKA: -1.36±0.10(Predicted)
• CAS DataBase Reference: METHYL6-METHOXY-2-PYRAZINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL6-METHOXY-2-PYRAZINECARBOXYLATE(23813-24-3)
• EPA Substance Registry System: METHYL6-METHOXY-2-PYRAZINECARBOXYLATE(23813-24-3)

Safety Data

• Hazardous Substances Data: 23813-24-3(Hazardous Substances Data)

Usage

General Description

Methyl 6-methoxy-2-pyrazinecarboxylate is a chemical compound with a molecular formula C9H9N3O3. It is a colorless to pale yellow liquid with a fruity, caramel-like odor. METHYL6-METHOXY-2-PYRAZINECARBOXYLATE is commonly used as a flavoring agent in the food and beverage industry, providing a roasted, nutty, or earthy aroma to products such as coffee, tea, cocoa, and various confectionery items. Additionally, it has been investigated for potential applications in pharmaceuticals and insect attractants due to its unique olfactory properties. Methyl 6-methoxy-2-pyrazinecarboxylate is considered safe for use in food and has been approved for use as a flavoring agent by regulatory agencies around the world.

InChI:InChI=1/C7H8N2O3/c1-11-6-4-8-3-5(9-6)7(10)12-2/h3-4H,1-2H3

Upstream product

• 124-41-4 sodium methylate 
• 6863-74-7 6-chloropyrazine-2-carbonitrile 
• 13924-99-7 6-oxo-1,6-dihydro-pyrazine-2-carboxylic acid 

Relevant articles and documents

Studies on pyrazine derivatives. XLIX. Synthesis and antibacterial activity of 6-methoxypyrazine-2-carboxylic acid hydrazide derivatives

The new 6-methoxy-pyrazine derivatives have been synthesized. 6-Methoxy-pyrazine-2-carboxylic acid hydrazide was used as an initial material to obtain mono- and dithioester of hydrazinecarbodithioic acid (2 and 3). Compound (2) in reaction with ethanolamine gave triazole derivative (8) with β-hydoxyethyl substituent in 4-position and hydroxyl group in 6-position of pyrazine ring. Dithioester (3) in a reaction with morpholine cyclized to 1,3,4-oxadiazole (11). The same substrate with alkyldiamines gave the few following derivatives: 1,3-diazacycloalkane derivatives (9 and 10), S-methyl-1,3,4-oxadiazole derivative (12) and 1,2,4-triazoletetrahydropyrimidine (13). The compounds obtained were tested in vitro for their activity towards pathogenic strains of anaerobic and aerobic bacteria. Derivative (9) was the most active against both types of tested strains.{A figure is presented}. 6-Methoxypyrazine-2-carboxylic Acid Hydrazide Hydrazinecarbodithioic Acid Ester Acid Ester 1,3,4-Oxadiazolethiol 1,2,4-Triazolethione.