2389-46-0

Basic information

• Product Name: BOC-LYS(Z)-ONP
• Synonyms: BOC-N-EPSILON-Z-L-LYSINE 4-NITROPHENYL ESTER;BOC-N-EPSILON-Z-L-LYSINE P-NITROPHENYL ESTER;BOC-LYSINE(Z)-ONP;BOC-LYS(Z)-ONP;N-ALPHA-BOC-N-EPSILON-BENZYLOXYCARBONYL-L-LYSINE P-NITROPHENYL ESTER;N-ALPHA-BOC-N-EPSILON-BENZYLOXYCARBONYL-L-LYSINE 4-NITROPHENYL ESTER;Boc-Lys(Cbz)-ONp;BOC-N-E-Z-L-LYSINE P-NITROPHENYLESTER
• CAS NO: 2389-46-0
• Molecular Formula: C₂₅H₃₁N₃O₈
• Molecular Weight: 501.53
• Product Categories: Amino Acid Derivatives;Amino Acids
• Mol File: 2389-46-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 89 °C(Solv: ethanol (64-17-5); water (7732-18-5)(1:1))
• Boiling Point: 676.9°Cat760mmHg
• Flash Point: 363.2°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 3.5E-18mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: -15°C
• PKA: 10.82±0.46(Predicted)
• CAS DataBase Reference: BOC-LYS(Z)-ONP(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-LYS(Z)-ONP(2389-46-0)
• EPA Substance Registry System: BOC-LYS(Z)-ONP(2389-46-0)

Safety Data

• Hazardous Substances Data: 2389-46-0(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow powder

InChI:InChI=1/C25H31N3O8/c1-25(2,3)36-24(31)27-21(22(29)35-20-14-12-19(13-15-20)28(32)33)11-7-8-16-26-23(30)34-17-18-9-5-4-6-10-18/h4-6,9-10,12-15,21H,7-8,11,16-17H2,1-3H3,(H,26,30)(H,27,31)

Upstream product

• 24498-31-5 (S)-methyl 2-amino-6-(benzyloxycarbonylamino)hexanoate 
• 1155-64-2 N₆-[(benzyloxy)carbonyl]-L-lysine 
• 56-87-1 L-lysine 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 100-02-7 4-nitro-phenol 
• 2389-45-9 Boc-Lys(Z)-OH 

Downstream Products

• 55592-81-9 N^ε-(benzyloxycarbonyl)-N^α-(tert-butoxycarbonyl)-L-lysinamide 
• 128404-12-6 (S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-3-hydroxy-propionic acid 
• 53195-68-9 N^α-BOC-N^ε-Z-Lys-Pro-OMe 
• 131697-08-0 Boc-Lys(Z)-Thr-Val-OMe 
• 129459-93-4 Lys-Tyr-Phe-Gln-Arg 
• 84047-89-2 (S)-2-[(S)-2-(2-{2-[(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid methyl ester 
• 32769-96-3 Boc-Lys(Z)-Lys(Z)-OBzl 
• 88759-19-7 Boc-Lys(Z)-Cys(MBzl)-Ser-Cys(MBzl)-Cys(MBzl)-Ala-OBzl 
• 88759-25-5 Boc-Lys(Z)-Gly-Ala-Ser-OMe 
• 88759-33-5 Boc-Lys(Z)-Cys(MBzl)-Ala-OBzl 
• 88831-93-0 Boc-Lys(Z)-Cys(MBzl)-Lys(Z)-OMe 
• 108562-98-7 Boc-Lys(Z)-Cys(MBzl)-NHMe 
• 108562-93-2 Boc-Lys(Z)-Pro-Gly-Gly-Cys(MBzl)-NHMe 
• 850427-69-9 Boc-L-Lys(Cbz)-N₁-spermine-Boc₃ 

Relevant articles and documents

A simple synthesis of imide-dipeptides

We report a simple approach to synthesize a new class of imide-dipeptides. This approach is mild, and the starting materials are the easily accessible amino acid derivatives. The imide-dipeptides were synthesized from the coupling of an amide and a 4-nitrophenyl activating ester of an amino acid. The acidic proton of the first amide was removed by 1 equivalent of n-butyl lithium to afford the corresponding amide anion which then reacted with the activating ester to give the desired imide derivatives. Georg Thieme Verlag Stuttgart.

Synthesis of peptides related to the C-terminus of B-peptide of ox co-fibrin (positions 16-21,15-21, and 13-21).

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