23974-15-4Relevant academic research and scientific papers
Syntheses of methylpyridine and methylpyridine N-oxide decorated benzoxazine and naphthoxazine platforms
Deck, Lorraine M.,Paine, Robert T.,Bright, Elizabeth R.,Ouizem, Sabrina,Dickie, Diane A.
, p. 2434 - 2437 (2014)
Simple, aqueous-based syntheses of methylpyridine and methylpyridine N-oxide decorated 3,4-dihydro-2H-naphthoxazine and 2,3-dihydro-1H-naphthoxazine monomers, as well as thermally promoted syntheses of 3,4-dihydro-2H-benzoxazine monomers and bisoxazine methylpyridine derivatives of substituted 1,5-, 2,6-, and 2,7-dihydroxynaphthalenes are described. The crystal structures of two derivatives are presented.
1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines
Chapman, Robert. S.L.,Tibbetts, Joshua. D.,Bull, Steven. D.
, p. 5330 - 5339 (2018/06/15)
1,1-Diacyloxy-1-phenylmethanes and 1-pivaloxy-1-acyloxy-1-phenylmethanes have been used as bench stable N-acylating reagents for primary and secondary amines and anilines under solvent-free conditions to afford their corresponding amides in good yield.
Construction of 1,2,4-Triazole Derivatives via Cyclocondensation of Alkylidene Dihydropyridines and Aryldiazonium Salts
Joshi, Madhur S.,Pigge, F.Christopher
supporting information, p. 5916 - 5919 (2016/11/29)
Alkylidene dihydropyridines (anhydrobases) prepared via dearomatization of N-acylated 4-(aminomethyl)pyridines participate in [3 + 2] cyclocondensation reactions with aryldiazonium cations to afford substituted 1,2,4-triazolium salts or neutral 1,2,4-tria
N -acyl DBN tetraphenylborate salts as N -acylating agents
Taylor, James E.,Jones, Matthew D.,Williams, Jonathan M. J.,Bull, Steven D.
experimental part, p. 2808 - 2818 (2012/04/23)
Air-stable and crystalline N-acyl DBN tetraphenylborate salts have been synthesized from 1,5-diazabicyclo[4.3.0]non-5-ene (DBN) and the corresponding acyl chloride in the presence of sodium tetraphenylborate. The salts have been shown to be effective N-acylating agents, reacting with primary amines, secondary amines, and sulfonamides to form the corresponding N-acylated products in good yields. The DBN hydrotetraphenylborate byproduct can be conveniently removed by filtration, providing pure N-acylated products without the need for further purification. The N-acyl DBN tetraphenylborate salts are attractive alternatives to acyl halides as they can be stored in air without decomposition, avoid the production of free acid during acylation reactions, and can be used under more forcing thermal conditions.
Hidden signatures: New reagents for developing latent fingerprints
Plater, M. John,Barnes, Paul,McDonald, Lauren K.,Wallace, Sandy,Archer, Nia,Gelbrich, Thomas,Horton, Peter N.,Hursthouse, Michael B.
experimental part, p. 1633 - 1641 (2009/06/28)
Aldehydes substituted with a quaternised pyridinium or quinolinium ring have been investigated for the development of latent fingerprints. Two routes were developed to a novel in situ formed azacyanine dye. This dye might form in the fingerprint where rea
SYNTHESIS OF N-BENZYL- AND N-HETEROARYLMETHYL-ACYLAMIDES BY REDUCTIVE N-ACYLATION OF ALDOXIMES WITH AMMONIUM FORMATE
Balicki, Roman,Kaczmarek, Lukasz
, p. 525 - 526 (2007/10/02)
Various (hetero)aryl aldoximes have been efficiently transformed to the corresponding acylamides via reductive N-acylation, catalyzed by 10percent palladium on carbon in the presence of ammonium formate as the hydrogen source in an alkanoic acid.
Analogues of platelet activating factor. 8. Antagonists of PAF containing an aromatic ring linked to a pyridinium ring
Trova,Wissner,Carroll,Kerwar,Pickett,Schaub,Torley,Kohler
, p. 580 - 590 (2007/10/02)
A series of platelet activating factor (PAF) antagonists containing a quaternary pyridinium ring connected through an amide, imide, or carbamate linkage to a substituted aromatic ring was prepared. Of these compounds, those containing a branched imide lin
Pyridinium compounds which are useful as antagonists of platelet activating factor
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, (2008/06/13)
The invention is aryl, amide, imide and carbamate pyridine antagonists of platelet activating factor.
Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
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, (2008/06/13)
1-(3- or 4-substituted piperidino)phthalazines of the formula wherein R is C1-6 alkyl; Y is a 3- or 4-position substituent and is -X-(CHR1)m-Z wherein R1 is hydrogen or C1-6 alkyl; m is 1 or 2; X is oxygen or a direct link provided that when m is 1, X is a direct link; and Z is -N(R2)COR3, -N(R2)COOR3, -N(R2)SO2R3, -N(R2)SO2NR4R5, -N(R2)SOR3, -N(R2)CONR4R5 or -OCONR4R5, wherein R2 and R5 are each independently hydrogen or C1-6 alkyl; R3 is C1-6 alkyl, phenethyl, benzyl, C3-7 cycloalkyl, phenyl or pyridyl; R4 is hydrogen or R3; provided that when X is a direct link, R3 or R4 is C3-7 cycloalkyl; the pharmaceutically acceptable acid addition salts thereof; processes for their preparation; and their use as cardiac stimulants and phosphodiesterase inhibitors
