2412-97-7Relevant academic research and scientific papers
Synthesis of new pyridines with oligocations and oxygen nucleophiles.
Schmidt, Andreas,Mordhorst, Thorsten,Habeck, Tobias
, p. 1375 - 1377 (2002)
Nucleophilic substitution of 4-(dimethylamino)pyridine on pentachloropyridine yielded pentakis(pyridine-2,3,4,5,6-pentayl)pyridinium, tris-(3,5-dichloropyridine-2,4,6-triyl)pyridinium, or (tetrachloropyridin-4-yl)pyridinium depending on the reaction conditions. Nucleophilic substitution with water, hydroxides, and alcoholates resulted in new betaines and highly substituted pyridines. [structure: see text]
Polyhalogenated heterocyclic compounds: Part 52. [1] Macrocycles from 3,5-dichloro-2,4,6-trifluoropyridine
Chambers, Richard D.,Khalil, Ali,Murray, Christopher B.,Sandford, Graham,Batsanov, Andrei S.,Howard, Judith A.K.
, p. 1002 - 1008 (2007/10/03)
Model studies show that displacement of fluorine, rather than chlorine, occurs upon reaction of 3,5-dichloro-2,4,6-trifluoropyridine with sodium methoxide and phenoxide. Subsequent hydro-dechlorination can be achieved by reaction with lithium aluminium hy
Synthesis of alkoxy-substituted pyridines from mono- and tricationic pyridinium salts
Schmidt, Andreas,Mordhorst, Thorsten
, p. 781 - 786 (2007/10/03)
Nucleophilic substitution reactions on 4-(4-dimethyl-amino)-pyridinium- substituted tetrachloropyridine with oxygen nucleophiles such as alkoxides and phenolates resulted in the formation of 4- or 2,4-alkoxy- or -phenoxy-substituted chloropyridines depend
Polyfluoroalkoxylation and methoxylation of polychloropyridines
Xu, Xiaoyong,Qian, Xuhong,Li, Zhong,Song, Gonghua
, p. 9 - 13 (2007/10/03)
With sodium 2,2,2-trifluoroethoxide, sodium 1,1,1,3,3,3-hexafluoro-2-propoxide and sodium methoxide used as nucleophilic reagents, the alcoholysis reactions of 2,3,4,5,6-pentachloropyridine and 2,3,5,6-tetrachloropyridine were studied. Some new polyfluoroalkoxypyridines have been synthesized. The activities, pathways, mechanism of the alcoholysis reactions are discussed.
