91591-88-7

Basic information

• Product Name: 2,4,6-Trimethoxypyridine
• Synonyms: 2,4,6-Trimethoxypyridine;Pyridine,2,4,6-trimethoxy-
• CAS NO: 91591-88-7
• Molecular Formula: C₈H₁₁NO₃
• Molecular Weight: 169.18
• Product Categories: Pyridines
• Mol File: 91591-88-7.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,4,6-Trimethoxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Trimethoxypyridine(91591-88-7)
• EPA Substance Registry System: 2,4,6-Trimethoxypyridine(91591-88-7)

Safety Data

• Hazardous Substances Data: 91591-88-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
2,4,6-Trimethoxypyridine is used as a key intermediate in the production of pharmaceuticals for its ability to facilitate the creation of diverse medicinal compounds.
Used in Agrochemical Production:
In the agrochemical industry, 2,4,6-Trimethoxypyridine is utilized as an intermediate to develop compounds that can enhance crop protection and management.
Used as a Potential Insect Repellent:
2,4,6-Trimethoxypyridine is studied for its potential use as an insect repellent due to its strong odor, which may contribute to the development of new insect control agents.
Environmental Considerations:
Given its classification as a potential environmental contaminant, the production, use, and disposal of 2,4,6-Trimethoxypyridine must be stringently regulated to mitigate its ecological impact.

Upstream product

• 16063-69-7 2,4,6-trichloropyridine 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 
• 2408-70-0 2,4,6-tribromopyridine 
• 2412-97-7 3,5-dichloro-2,4,6-trimethoxypyridine 
• 1737-93-5 3,5-dichloro-2,4,6-trifluoropyridine 
• 2402-78-0 2,6-dichloropyridine 
• 2587-00-0 2,6-dichloropyridine N-oxide 
• 2587-02-2 2,6-dichloro-[4]pyridylamine 
• 18677-55-9 2,4,6-trimethoxypyridine N-oxide 

Downstream Products

• 2412-97-7 3,5-dichloro-2,4,6-trimethoxypyridine 
• 797050-70-5 (1-benzyl-1H-indol-3-yl)-(4-hydroxy-6-methoxy-2-methyl-pyridin-3-yl)-methanone 
• 797050-69-2 (1-benzyl-1H-indol-3-yl)-(4,6-dimethoxy-2-methyl-pyridin-3-yl)-methanone 
• 797050-68-1 1-benzyl-3-(4,6-dimethoxy-2-trifluoromethanesulfonyloxynicotinoyl)indole 
• 797050-67-0 1-benzyl-3-(2-hydroxy-4,6-dimethoxynicotinoyl)indole 
• 797050-66-9 1-benzyl-3-(2,4,6-trimethoxynicotinoyl)indole 
• 872171-02-3 1-(1-benzyl-3-indolyl)-1-(6-methoxy-4-trifluoromethanesulfonyloxy-3-pyridinyl)ethane 
• 872170-96-2 1-benzyl-3-(4-hydroxy-2,6-dimethoxynicotinoyl)indole 
• 872170-99-5 1-benzyl-3-(4-hydroxy-6-methoxynicotinoyl)indole 
• 872171-00-1 1-(1-benzyl-3-indolyl)-1-(4-hydroxy-6-methoxy-3-pyridinyl)ethene 
• 872170-98-4 1-benzyl-3-(4,6-dimethoxynicotinoyl)indole 
• 872171-01-2 1-(1-benzyl-3-indolyl)-1-(4-hydroxy-6-methoxy-3-pyridinyl)ethane 
• 797050-65-8 1-benzyl-3-(2,4,6-trimethoxynicotinoyl)indole-2-carboxylic acid 

Relevant articles and documents

Ligand-promoted ortho-C-H amination with Pd catalysts

2,4,6-Trimethoxypyridine is identified as an efficient ligand for promoting a Pd-catalyzed ortho-C-H amination of both benzamides and triflyl-protected benzylamines. This finding provides guidance for the development of ligands that can improve or enable PdII-catalyzed Csp2-H activation reactions directed by weakly coordinating functional groups.

Polyhalogenated heterocyclic compounds: Part 52. [1] Macrocycles from 3,5-dichloro-2,4,6-trifluoropyridine

Model studies show that displacement of fluorine, rather than chlorine, occurs upon reaction of 3,5-dichloro-2,4,6-trifluoropyridine with sodium methoxide and phenoxide. Subsequent hydro-dechlorination can be achieved by reaction with lithium aluminium hy

Herbicidal cyclohexane-1,3-dione derivatives

The invention concerns novel compounds of the formula I STR1 wherein: Z is selected from oxygen and the group --YAn wherein Y is selected from C1 to C6 alkyl and benzyl and An is an anion; k is zero or the integer 1; n is an integer selected from 3 and 4; X is selected from halogen, nitro, cyano, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, alkenyl, alkenyloxy, alkynyl, alkynyloxy, acyloxy, alkoxycarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl, sulfamoyl, substituted sulfamoyl, alkanoyloxy, benzyloxy, substituted benzyloxy, amino, substituted amino and the groups formyl and alkanoyl and the oxime, imine and Schiff base derivatives thereof; R1 is selected from hydrogen, alkyl, alkenyl, alkynyl, substituted alkyl, alkylsulfonyl, arylsulfonyl, acyl and an inorganic or organic cation; R2 is selected from alkyl, substituted alkyl, alkenyl, haloalkenyl, alkynyl and haloalkynyl; R3 is selected from alkyl, fluoroalkyl, alkenyl, alkynyl, and phenyl; and R4 is selected from hydrogen, halogen, alkyl, cyano and alkoxycarbonyl. The compounds of the invention show herbicidal properties and plant growth regulating properties and in further embodiments the invention provides processes for the preparation of compounds of formula I, intermediates useful in the preparation of the compounds of formula I, compositions containing as active ingredient a compound of formula I, and herbicidal and plant growth regulating processes utilizing compounds of formula I.

Novel Annelation Method to Pyridine and Isoquinoline by Photochemical Means

Intramolecular photoaddition reactions of 2-(ω-alkenyl)isoquinolin-1(2H)-ones and 1-(ω-alkenyl)pyridin-2(1H)-ones were examined, and the regioselectivity and dependence of these reactions on the length of methylene chain in the alkenyl group were clarified.By utilizing these reactions, a synthetic route to indolizine and quinolizine derivates was elaborated.By an extension of this approach to the intermolecular reaction, 6-methoxy-3-methyl-1,2-dihydrocyclobutapyridin-4(3H)-one was synthesized from 4,6-dimethoxy-1-methylpyridin-2(1H)-one.Keywords-2+2 photocycloaddition; intramolecular photoaddition; photocycloreversion; annelation; indolizine; quinolizine; cyclobutapyridine; 4,6-dimethoxypyridin-2(1H)-one; 1-(ω-alkenyl)pyridin-2(1H)-one; 2-(ω-alkenyl)isoquinolin-1(2H)-one