24133-46-8

Usage

Uses

Used in Pharmaceutical Industry:
2-Isobutoxyacetic Acid is used as an intermediate in the synthesis of bicyclic bridged cycloalkane derivatives. These derivatives serve as inhibitors of the ATF4 pathway, which plays a crucial role in various cellular processes, including stress response, metabolism, and cell differentiation. Inhibiting the ATF4 pathway can have therapeutic applications in treating certain diseases and conditions.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Isobutoxyacetic Acid can be utilized as a building block for the creation of more complex organic molecules. Its unique structure allows for various chemical reactions, such as esterification, amidation, and substitution, making it a versatile compound for the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.

InChI:InChI=1/C6H12O3/c1-5(2)3-9-4-6(7)8/h5H,3-4H2,1-2H3,(H,7,8)

Upstream product

• 135291-86-0 isobutoxy-acetonitrile 
• 13361-35-8 isobutyl chloroacetate 
• 13259-29-5 sodium isobutoxide 
• 79-11-8 chloroacetic acid 
• 78-83-1 2-methyl-propan-1-ol 
• 105-36-2 ethyl bromoacetate 
• 3926-62-3 sodium monochloroacetic acid 

Downstream Products

• 34180-11-5 chloromethyl isobutyl ether 
• 56680-72-9 isobutoxy-acetyl chloride 
• 140472-28-2 isobutyl isobutoxyacetate 

Relevant academic research and scientific papers

PYRROLOPYRIDAZINE DERIVATIVES

The invention relates to compound of the formula (I) or its salt, in which R1, R2, R3 and R4 are as defined in the description, their use of as medicament, the process for their preparation and use for the treatment of PDE-IV or TNF-α mediated diseases.

Synthesis of N-[2-(2-methylpropoxy)ethyl]-N-{2-[(4-methoxy) phenylmethylthio]phenyl}-1-pyrrolidineethanamine (E)-2-butenedioate (1:1) salt (CERM 12816): A potential anti-anginal drug

CERM 12816, which was required for metabolic studies, was labelled with [14C] in the methylene carbon of the benzyl group. This involved eight steps starting from barium [14C] carbonate and 4-methoxyphenylmagnesium bromide, with a 20

Process for preparation of α-alkoxy acetic acids and their salts

A process for producing an α-alkoxy acetic acids and salts thereof which comprises reacting an alcohol of the formula R--OH wherein R is alkyl, substituted alkyl, or cycloalkyl, or cycloalkyl alkyl with a base in an aprotic organic solvent to give an alko

SULFURIC ACID CATALYZED DECARBONYLATION OF ALKOXYACETYL CHLORIDES

Sulfuric acid catalyzes the decarbonylation of alkoxyacetyl chlorides to produce the corresponding chloromethyl alkyl ethers in fairly good yields.