241478-40-0

Basic information

• Product Name: tert-butyl (1S,2R,3E)-N-[2-hydroxy-1-(hydroxymethyl)-4-phenyl-3-butenyl]carbamate
• Synonyms: tert-butyl (1S,2R,3E)-N-[2-hydroxy-1-(hydroxymethyl)-4-phenyl-3-butenyl]carbamate
• CAS NO: 241478-40-0
• Molecular Weight: 293.363
• Mol File: 241478-40-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: tert-butyl (1S,2R,3E)-N-[2-hydroxy-1-(hydroxymethyl)-4-phenyl-3-butenyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (1S,2R,3E)-N-[2-hydroxy-1-(hydroxymethyl)-4-phenyl-3-butenyl]carbamate(241478-40-0)
• EPA Substance Registry System: tert-butyl (1S,2R,3E)-N-[2-hydroxy-1-(hydroxymethyl)-4-phenyl-3-butenyl]carbamate(241478-40-0)

Safety Data

• Hazardous Substances Data: 241478-40-0(Hazardous Substances Data)

Upstream product

• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 154437-24-8 tert-butyl (4S)-4-[(1R,2E)-1-hydroxy-3-phenyl-2-propenyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 
• 536-74-3 phenylacetylene 
• 241478-36-4 tert-butyl-(1S,2R)-N-[2-hydroxy-1-(hydroxymethyl)-3-phenylacetylenyl]carbamate 
• 870-50-8 di-tert-butyl-diazodicarboxylate 
• 95728-97-5 (E)-ethyl 3-hydroxy-5-phenylpent-4-enoate 
• 89426-28-8 (2R,3R)-2,3-epoxypent-4-yn-1-ol 
• 35042-52-5 (E)-2-penten-4-yn-1-ol 
• 1332569-78-4 (R)-1-((S)-2-oxooxazolidin-4-yl)prop-2-ynyl benzoate 
• 1332569-93-3 (S)-tert-butyl 4-((R)-1-(benzoyloxy)-3-phenylprop-2-ynyl)-2-oxooxazolidine-3-carboxylate 
• 1332569-82-0 (R)-1-((S)-2-oxooxazolidin-4-yl)-3-phenylprop-2-ynyl benzoate 
• 4440-01-1 lithium phenylacetylide 
• 241478-33-1 tert-butyl (4S)-4-<(1R)-1-hydroxy-3-phenyl-2-propynyl>-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 

Downstream Products

• 241478-48-8 (2S,3R,4E)-2-amino-5-phenyl-4-pentene-1,3-diol 
• 254434-46-3 ((1S,2S)-2-Hydroxy-1-hydroxymethyl-4-phenyl-butyl)-carbamic acid tert-butyl ester 
• 254434-45-2 ((1S,2R)-2-Hydroxy-1-hydroxymethyl-4-phenyl-butyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Synthesis of aromatic sphingosine analogues by diastereoselective amination of enantioenriched trans-γ,δ-unsaturated β-hydroxyesters

An effective route to N-Boc-protected aromatic sphingosine analogues is accomplished. The strategy is based on the diastereoselective amination of enantioenriched trans-γ,δ-unsaturated β-hydroxyesters to establish anti,N-Boc-α-hydrazino-β-hydroxyesters. N

Synthesis and biological properties of novel sphingosine derivatives

Sphingosine-1-phosphate (S-1P) derivatives such as threo-(2S,3S)-analogues, which are C-3 stereoisomers of natural erythro-(2S,3R)-S-1P, have been synthesized starting from l-serine or (1S,2S)-2-amino-1-aryl-1,3-propanediols (6). threo-(1S,2R)-2-Amino-1-aryl-3-bromopropanols (HBr salt) have also been prepared from 6. The threo-S-1Ps and the threo-amino-bromide derivatives have shown potent inhibitory activity against Ca2+ ion mobilization in HL60 cells induced by erythro-S-1P, suggesting that these compounds would compete with cell surface EDG/S1P receptors.

Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons

A series of D-erythro- and L-threo-ceramide analogues was synthesized and investigated for their ability to reverse the inhibitory effects of fumonisin B1 (FB1) on axonal growth in hippocampal neurons. The analogues contained either