24152-44-1

Basic information

• Product Name: (4-butylpiperidin-1-yl)(phenyl)methanone
• Synonyms: (4-butylpiperidin-1-yl)(phenyl)methanone
• CAS NO: 24152-44-1
• Molecular Weight: 245.365
• Mol File: 24152-44-1.mol

Chemical Properties

• CAS DataBase Reference: (4-butylpiperidin-1-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-butylpiperidin-1-yl)(phenyl)methanone(24152-44-1)
• EPA Substance Registry System: (4-butylpiperidin-1-yl)(phenyl)methanone(24152-44-1)

Safety Data

• Hazardous Substances Data: 24152-44-1(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 98-88-4 benzoyl chloride 
• 181219-01-2 4-pyridineboronic acid pinacol ester 
• 65-85-0 benzoic acid 
• 80213-01-0 (4-hydroxy-1-piperidinyl)(phenyl)methanone 
• 109-65-9 1-bromo-butane 
• 122374-26-9 1-Benzoyl-4-bromopiperidine 

Relevant articles and documents

Synthesis and utility of dihydropyridine boronic esters

When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine products.

Nickel-catalyzed cross-coupling of unactivated alkyl halides using bis(pinacolato)diboron as reductant

The use of bis(pinacolato)diboron as the terminal reductant allows the efficient Ni-catalyzed coupling of unactivated secondary and primary alkyl halides, generating the C(sp3)-C(sp3) coupling products in good yields. The mild cataly

Nickel-Catalyzed reductive cross-Coupling of unactivated alkyl halides

A Ni-catalyzed reductive approach to the cross-coupling of two unactivated alkyl halides has been successfully developed. The reaction works efficiently for primary and secondary halides, with at least one being bromide. The mild reaction conditions allow for excellent functional group tolerance and provide the C(sp3)-C(sp3) coupling products in moderate to excellent yields.