2421-61-6

Basic information

• Product Name: Glycine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, methyl ester
• CAS NO: 2421-61-6
• Molecular Formula: C16H22N2O5
• Molecular Weight: 322.361
• Mol File: 2421-61-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Glycine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, methyl ester(2421-61-6)
• EPA Substance Registry System: Glycine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, methyl ester(2421-61-6)

Safety Data

• Hazardous Substances Data: 2421-61-6(Hazardous Substances Data)

Usage

General Description

Glycine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, methyl ester is a chemical compound often used in pharmaceutical research and drug development. It is a methyl ester derivative of the amino acid glycine, and contains a valine residue with a phenylmethoxy carbonyl group attached. Glycine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, methyl ester can be used as a building block in the synthesis of peptides and proteins, and is commonly employed in the production of pharmaceutical drugs and biotechnology products. It is important in the field of medicinal chemistry and drug discovery, as it can be used to design and create new drugs with specific molecular properties and pharmacological activities. Additionally, this compound has potential applications in fields such as biochemistry, molecular biology, and drug delivery.

Upstream product

• 3496-11-5 2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 616-34-2 methoxycarbonylmethylamine 
• 501-53-1 benzyl chloroformate 
• 91285-93-7 1-Benzyloxycarbonylbenzimidazoline-2-thione 
• 91285-92-6 N-(benzyloxycarbonyl)benzothiazolin-2-thione 
• 91285-91-5 benzyl 2-thioxobenzo[d]oxazol-3(2H)-carboxylate 
• 91285-94-8 O-benzyl S-(pyridin-2-yl)carbonothioate 
• 72-18-4 L-valine 
• 67-56-1 methanol 
• 100803-88-1 3-(N-Benzyloxycarbonyl-L-valyl)-benzoxazoline-2-thione 
• 54647-77-7 N-[(benzyloxy)carbonyl]-L-valine, compound with dicyclohexylamine (1:1) 
• 126814-51-5 N-(Benzyloxycarbonyl)-L-valine 1H-benzotriazol-1-yl ester 

Downstream Products

• 16944-60-8 (2S)-isopropylpiperazine-3,6-dione 
• 686-43-1 valylglycine 
• 133181-65-4 (S)-1,4-di-(benzyloxycarbonyl)-2-isopropylpiperazine 
• 84468-53-1 (S)-2-isopropylpiperazine 
• 89092-73-9 Z-Val-Val-Gly-OMe 
• 22221-75-6 N-(N-benzyloxycarbonyl-L-valyl)-glycine 

Relevant articles and documents

A novel reagent (N_succinimidyl diphenylphosphate) for synthesis of active ester and peptide

N-succinimidyl diphenylphosphate (SDPP) was prepared. This reagent was useful for the preparation of active esters and peptides in stead of dicyclohexylcarbodiimide.

Temperature, pH and H-bond synergism for peptide bond formation: Synthesis of sequence specific tetra- and penta-peptides without using coupling reagent

A reaction temperature of 120°C, pH of 5.0 and reaction time of 6 h were chosen as the best conditions for the condensation of two nonactivated amino acids to form a peptide bond. Role of H-bond in these reactions was anticipated. The method was validated

N-tert-Butylglyoxylicamide, the New Reagent for Peptide Segment Coupling by Four-Component Reaction

In contrast to the use of other aldehyd components, the Tetra Component Reactions (4CR) of carboxyl acids and primary amines with combinations of N-tert-butylglyoxylicamide and isocyanides produce carbonamides that yield the desired stereochemically unifo