24258-38-6Relevant academic research and scientific papers
Synthesis and evaluation of antibacterial activities of 5,7-dihydroxycoumarin derivatives
Chin, Yi-Ping,Huang, Wei-Jan,Hsu, Feng-Lin,Lin, Mei-Hsiang,Lin, Yuh-Ling
, p. 386 - 393 (2012/01/11)
This study examines the synthesis and antibacterial activities of 5,7-dihydroxycoumarin derivatives, whose structures were confirmed using analytical and spectral data. Twenty compounds were tested for their antibacterial activities against five microbial species such as E. coli, S. aureus, K. pneumonia, P. aeruginosa, and S. typhimurium were studied. Compounds 5 and 12 exhibited the most potent activity against Staphylococcus aureus with a MIC value of 2.5 μg/mL for each of the compounds. Copyright
An efficient ZrCl4 catalyzed one-pot solvent free protocol for the synthesis of 4-substituted coumarins
Sharma,Janardhan Reddy,Sree Lakshmi,Radha Krishna
, p. 6119 - 6121 (2007/10/03)
A versatile and efficient route to 4-substituted coumarins via a Pechmann reaction using ZrCl4 as the catalyst (10 mol %) is described. This method provides several advantages over alternative procedures such as mild, solvent-free conditions at ambient temperature, and direct isolation of the products in high yields.
