2428-41-3

Usage

Class

Indene derivatives

Explanation

Indene derivatives are a group of organic compounds derived from the indene molecule, which is a type of aromatic hydrocarbon. 1-(4-methoxybenzylidene)-1H-indene is a member of this class.

Explanation

The compound exists in a solid state and has a yellow color. It forms crystals, which are solid structures with a well-defined geometric shape.

Explanation

The molecular weight is the mass of one mole of a substance, in this case, 1-(4-methoxybenzylidene)-1H-indene. It is calculated by adding the atomic weights of all the atoms in the molecule.

Explanation

The melting point is the temperature at which a solid substance transitions into a liquid state. For 1-(4-methoxybenzylidene)-1H-indene, this transition occurs between 126 and 127 degrees Celsius.

Explanation

The boiling point is the temperature at which a liquid substance transitions into a gaseous state. For 1-(4-methoxybenzylidene)-1H-indene, this transition occurs between 381 and 383 degrees Celsius.

Explanation

1-(4-methoxybenzylidene)-1H-indene is used in the field of organic synthesis, which involves the study and construction of carbon-containing compounds.

Explanation

The compound is commonly used as an intermediate in the production of various pharmaceuticals and agrochemicals due to its versatile reactivity and functional group compatibility.

Explanation

1-(4-methoxybenzylidene)-1H-indene is utilized as a building block in the synthesis of complex organic molecules with valuable properties, such as those with potential applications in various industries.

Physical state

Yellow crystalline solid

Molecular weight

234.29 g/mol

Melting point

126-127 °C

Boiling point

381-383 °C

Application

Organic synthesis

Intermediate in pharmaceuticals and agrochemicals

Yes

Building block in complex organic molecules

Yes

Upstream product

• 64-18-6 formic acid 
• 861567-32-0 inden-1-yl-(4-methoxy-phenyl)-methanol 
• 123-11-5 4-methoxy-benzaldehyde 
• 15719-64-9 methylammonium carbonate 
• 95-13-6 1-indene 
• 7647-01-0 hydrogenchloride 
• 67-56-1 methanol 
• 64-17-5 ethanol 

Downstream Products

• 101596-41-2 1-(p-methoxy benzyl)indene 
• 109877-29-4 tricarbonyl(1,2,1',2',3',4'-η-6-(p-methoxyphenyl)-1,2-benzofulvene)chromium 

Relevant academic research and scientific papers

The effect of substitution on the cytotoxicity of molybdenum(II) and tungsten(II) compounds

A series of allyl molybdenum [(η3-C3H 5)Mo(CO)2L2Cl], [(η3-C 3H4COOMe)Mo(CO)2L2Br], cyclopentadienyl molybdenum [(η5-C5H s

The Missing C1-C5 Cycloaromatization Reaction: Triplet State Antiaromaticity Relief and Self-Terminating Photorelease of Formaldehyde for Synthesis of Fulvenes from Enynes

The last missing example of the four archetypical cycloaromatizations of enediynes and enynes was discovered by combining a twisted alkene excited state with a new self-terminating path for intramolecular conversion of diradicals into closed-shell products. Photoexcitation of aromatic enynes to a twisted alkene triplet state creates a unique stereoelectronic situation, which is facilitated by the relief of excited state antiaromaticity of the benzene ring. This enables the usually unfavorable 5-endo-trig cyclization and merges it with 5-exo-dig closure. The 1,4-diradical product of the C1-C5 cyclization undergoes internal H atom transfer that is coupled with the fragmentation of an exocyclic C-C bond. This sequence provides efficient access to benzofulvenes from enynes and expands the utility of self-terminating aromatizing enyne cascades to photochemical reactions. The key feature of this self-terminating reaction is that, despite the involvement of radical species in the key cyclization step, no external radical sources or quenchers are needed to provide the products. In these cascades, both radical centers are formed transiently and converted to the closed-shell products via intramolecular H-transfer and C-C bond fragmentation. Furthermore, incorporating C-C bond cleavage into the photochemical self-terminating cyclizations of enynes opens a new way for the use of alkenes as alkyne equivalents in organic synthesis.

Ultrasonicated condensation of indene and 2-nitrofluorene with aromatic aldehydes catalyzed by bis-(p-methoxyphenyl)telluroxide (BMPTO)

The condensation of indene or 2-nitrofluorene with aromatic aldehydes catalyzed by bis-(p-methoxyphenyl)telluroxide (BMPTO) under ultrasonic wave irradiation gave corresponding fulvenes in fair to good yield.

KF-Al2O3 induced condensations of indene with aromatic aldehydes

In the presence of KF-Al2O3 as a solid catalyst, indene reacted with aromatic aldehydes 2a-c (R=4-Me, 4-MeO, 4-Me2N) to yield mainly benzofulvenes 3a-c (45%-66%), while when treated with two molar of aromatic aldehydes 2d-