243462-89-7

Upstream product

• 678149-54-7 3-(2,5-dimethoxy-4-methylphenyl)but-2-enol 
• 678149-59-2 4-(2,5-dimethoxy-4-methylphenyl)-4,5,5-trimethyl-cyclopent-2-enone 
• 243117-89-7 dimethyl 2,2,3-trimethyl-3-(2,5-dimethoxy-4-methylphenyl)adipate 
• 243117-88-6 2-(7-methoxy-5,8-dimethyl-2-oxo-2,3,4,5-tetrahydro-benzo[b]oxepin-5-yl)-2-methyl-propionic acid methyl ester 
• 868157-03-3 1-(2,5-dimethoxy-4-methyl-phenyl)-2,2-dimethyl-cyclopent-3-enecarboxylic acid methyl ester 
• 878774-45-9 [1-(2,5-dimethoxy-4-methyl-phenyl)-2,2-dimethyl-cyclopent-3-enyl]-methanol 
• 878774-36-8 1-(2,5-dimethoxy-4-methyl-phenyl)-2,2-dimethyl-cyclopent-3-enecarbaldehyde 
• 864934-97-4 2-allyl-3-(2,5-dimethoxy-4-methyl-phenyl)-3-methyl-pent-4-enoic acid ethyl ester 
• 864934-98-5 2-(2,5-dimethoxy-4-methyl-phenyl)-2-methyl-cyclopent-3-enecarboxylic acid ethyl ester 
• 678149-60-5 ethyl 3-methyl-3-(2,5-dimethoxy-4-methylphenyl)-pent-4-enoate 
• 878774-22-2 3,3,4-trimethyl-4-(2,5-dimethoxy-4-methylphenyl)cyclopentene 
• 243117-90-0 (+/-)-3-(2,5-dimethoxy-4-methylphenyl)-2,2,3-trimethylcyclopentanone 
• 868156-99-4 2-allyl-2-(2,5-dimethoxy-4-methyl-phenyl)-3,3-dimethyl-pent-4-enoic acid methyl ester 

Downstream Products

• 66389-30-8 5-methyl-2-(1,2,2-trimethylcyclopentyl)benzene-1,4-diol 
• 864934-94-1 4-acetoxy-5-methyl-2-(1,2,2-trimethylcyclopentyl)phenyl acetate 
• 28917-12-6 (+/-)-cuparene-1,,4-quinone 
• 864934-77-0 4-methoxy-5-methyl-2-(1,2,2-trimethylcyclopentyl)phenol 

Relevant academic research and scientific papers

Total synthesis of enokipodins A-D and cuparene-1 ,4-diol

A Claisen rearrangement and RCM reaction based sequence has been developed for total synthesis of the antifungal sesquiterpenes enokipodins A-D and cuparene-1 ,4-diol starting from 2,5-dimethoxy-4-methythydroquinone. Copyright

The first total synthesis of (±)-lagopodin A

The first total synthesis of (±)-lagopodin A and a formal total synthesis of enokipodins A and B is described. The requisite precursors containing two vicinal quaternary carbon atoms were assembled employing Claisen rearrangement and an RCM reaction as ke

Total synthesis of HM-1 and HM-2, aromatic sesquiterpenes isolated from the phytopathogenic fungus Helicobasidium mompa. Structure revision of HM-2

The structure assigned to the sesquiterpene HM-2 was found to be incorrect by total synthesis. A ring-closing metathesis based strategy was developed for the total synthesis of the aromatic sesquiterpene HM-1, which on functional group transformation established the structure of HM-2 as 23, a cuparene derivative.

The First Total Synthesis of the Antimicrobial Sesquiterpenes (±)-Enokipodins A and B

Efficient first total synthesis of antimicrobial sesquiterpenes enokipodins A and B (1 and 2, respectively) and formal total synthesis of cuparene-1,4-diol (5) and cuparene-1,4-quinone (7) have been accomplished starting from 2,5-dimethoxy-4-methyl-acetop

Facile total synthesis of (±)-α-herbertenol, (±)-1,4-cuparenediol and (±)-cuparene-1,4-quinone

The total syntheses of the bicyclic sesquiterpene phenols (±)-α-herbertenol (1) and (±)-1,4-cuparenediol (2) have been successfully accomplished involving copper-catalysed conjugate addition of Grignard reagents to unsaturated dinitriles and α,α-dimethyla

Facile total synthesis of (±)-α-herbertenol, (±)-α-cuparenone and (±)-HM-1 methyl ether involving alkylation of hindered esters

The total syntheses of (±)-α-herbertenol 1, (±)-α-cuparenone 4 and (±)-HM-1 methyl ether 3 have been successfully accomplished involving α,α- dimethylation of the esters 8a, 17 and 8b respectively as key steps.