864934-77-0

Upstream product

• 243462-89-7 1-(2,5-dimethoxy-4-methylphenyl)-1,2,2-trimethyl-cyclopentane 
• 66389-30-8 5-methyl-2-(1,2,2-trimethylcyclopentyl)benzene-1,4-diol 
• 74-88-4 methyl iodide 
• 678149-54-7 3-(2,5-dimethoxy-4-methylphenyl)but-2-enol 
• 243117-89-7 dimethyl 2,2,3-trimethyl-3-(2,5-dimethoxy-4-methylphenyl)adipate 
• 243117-88-6 2-(7-methoxy-5,8-dimethyl-2-oxo-2,3,4,5-tetrahydro-benzo[b]oxepin-5-yl)-2-methyl-propionic acid methyl ester 
• 243117-90-0 (+/-)-3-(2,5-dimethoxy-4-methylphenyl)-2,2,3-trimethylcyclopentanone 
• 864934-94-1 4-acetoxy-5-methyl-2-(1,2,2-trimethylcyclopentyl)phenyl acetate 
• 864934-97-4 2-allyl-3-(2,5-dimethoxy-4-methyl-phenyl)-3-methyl-pent-4-enoic acid ethyl ester 
• 864934-98-5 2-(2,5-dimethoxy-4-methyl-phenyl)-2-methyl-cyclopent-3-enecarboxylic acid ethyl ester 
• 678149-60-5 ethyl 3-methyl-3-(2,5-dimethoxy-4-methylphenyl)-pent-4-enoate 

Downstream Products

• 28917-12-6 (+/-)-cuparene-1,,4-quinone 

Relevant academic research and scientific papers

Total synthesis of HM-1 and HM-2, aromatic sesquiterpenes isolated from the phytopathogenic fungus Helicobasidium mompa. Structure revision of HM-2

The structure assigned to the sesquiterpene HM-2 was found to be incorrect by total synthesis. A ring-closing metathesis based strategy was developed for the total synthesis of the aromatic sesquiterpene HM-1, which on functional group transformation established the structure of HM-2 as 23, a cuparene derivative.

Facile total synthesis of (±)-α-herbertenol, (±)-1,4-cuparenediol and (±)-cuparene-1,4-quinone

The total syntheses of the bicyclic sesquiterpene phenols (±)-α-herbertenol (1) and (±)-1,4-cuparenediol (2) have been successfully accomplished involving copper-catalysed conjugate addition of Grignard reagents to unsaturated dinitriles and α,α-dimethyla